盐酸去氧肾上腺素

盐酸去氧肾上腺素结构式
盐酸去氧肾上腺素结构式
品牌特惠专场
常用名 盐酸去氧肾上腺素 英文名 Phenylephrine hydrochloride
CAS号 61-76-7 分子量 203.666
密度 N/A 沸点 341.1ºC at 760 mmHg
分子式 C9H14ClNO2 熔点 143-145 °C(lit.)
MSDS 中文版 美版 闪点 163.4ºC
符号 GHS07
GHS07
信号词 Warning

Receptor mediated disruption of retinal pigment epithelium function in acute glycated-albumin exposure.

Exp. Eye Res. 137 , 50-6, (2015)

Diabetic macular edema (DME) is a major cause of visual impairment. Although DME is generally believed to be a microvascular disease, dysfunction of the retinal pigment epithelium (RPE) can also contribute to its development. Advanced glycation end-products (...

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ...

Formulation and stability study of a pediatric 2% phenylephrine hydrochloride eye drop solution.

Ann. Pharm. Fr. 73(1) , 31-6, (2015)

We present formulation and stability evaluation of a 2% (w/v) phenylephrine hydrochloride biocompatible eye drop solution, routinely prepared in hospital pharmacy under aseptic conditions, for retinal examination of neonates and premature infants.Eye drop sol...

Altered energy state reversibly controls smooth muscle contractile function in human saphenous vein during acute hypoxia-reoxygenation: Role of glycogen, AMP-activated protein kinase, and insulin-independent glucose uptake.

Biochem. Pharmacol. 97 , 77-88, (2015)

Hypoxia is known to promote vasodilation of coronary vessels through several mediators including cardiac-derived adenosine and endothelium-derived prostanoids and nitric oxide. To date, the impact of endogenous glycogen depletion in vascular smooth muscle and...

The association between macular thickness and peripapillary retinal nerve fiber layer thickness in Chinese children.

Medicine (Baltimore.) 94(8) , e567, (2015)

To investigate the association between macular thickness and peripapillary retinal nerve fiber layer (RNFL) thickness in Chinese children. This cross-sectional study recruited consecutive cases of healthy pediatric subjects aged 4 to 18 from Caritas Medical C...

Retinal nerve fiber layer thickness in myopic, emmetropic, and hyperopic children.

Medicine (Baltimore.) 94(12) , e699, (2015)

The purpose of this study was to investigate the peripapillary retinal nerve fiber layer (RNFL) thickness in myopic, emmetropic, and hyperopic children using optical coherence tomography. Two-hundred one right eyes of subjects aged 4 to 18 years were divided ...

Noradrenergic modulation of the parallel fiber-Purkinje cell synapse in mouse cerebellum.

Neuropharmacology 89 , 33-42, (2014)

The signals arriving to Purkinje cells via parallel fibers are essential for all tasks in which the cerebellum is involved, including motor control, learning new motor skills and calibration of reflexes. Since learning also requires the activation of adrenerg...

Functional evaluation using multifocal electroretinogram after selective retina therapy with a microsecond-pulsed laser.

Invest. Ophthalmol. Vis. Sci. 56(1) , 122-31, (2015)

To evaluate the changes of retinal function with multifocal electroretinogram (mfERG), and estimate the association between functional and structural changes after selective retina therapy (SRT) with microsecond-pulsed laser in comparison to continuous wave l...

Intraocular pharmacokinetics of intravitreal vascular endothelial growth factor-Trap in a rabbit model.

Eye (Lond.) 29(4) , 561-8, (2015)

To determine intraocular pharmacokinetic properties of intravitreally injected vascular endothelial growth factor (VEGF)-Trap in a rabbit model.VEGF-Trap was intravitreally injected in 18 rabbit eyes. Eyes were enucleated 1 h and 1, 2, 5, 14, and 30 days afte...

Lipophilicity of amine neurotransmitter precursors, metabolites and related drugs estimated on various TLC plates.

J. Chromatogr. Sci. 52(9) , 1095-103, (2014)

The retention behavior for a series of amine neurotransmitters, their precursors, metabolites and structurally related drugs has been investigated in reversed-phase thin-layer chromatography using RP-18, RP-8, RP-2, CN and Diol stationary phases and mixtures ...