白藜芦醇

白藜芦醇结构式
白藜芦醇结构式
品牌特惠专场
常用名 白藜芦醇 英文名 Resveratrol
CAS号 501-36-0 分子量 228.243
密度 1.4±0.1 g/cm3 沸点 449.1±14.0 °C at 760 mmHg
分子式 C14H12O3 熔点 253-255°C
MSDS 中文版 美版 闪点 222.3±14.7 °C
符号 GHS07
GHS07
信号词 Warning

Mitochondrial impairment triggers cytosolic oxidative stress and cell death following proteasome inhibition.

Sci. Rep. 4 , 5896, (2014)

Dysfunctions of the mitochondria and the ubiquitin-proteasome system, as well as generation of reactive oxygen species (ROS), are linked to many aging-related neurodegenerative disorders. However, the order of these events remains unclear. Here, we show that ...

Phytoestrogens induce differential effects on both normal and malignant human breast cells in vitro.

Climacteric 17(6) , 682-91, (2014)

To explore the effect and pathway of phytoestrogens in vitro on the growth of both normal and malignant breast cells.Normal breast MCF-10A cells and breast cancer MCF-7 cells were incubated with 10 (-10)-10(-4)  mol/l genistein, resveratrol, and quercetin (pl...

Assessment of the potential of polyphenols as a CYP17 inhibitor free of adverse corticosteroid elevation.

Biochem. Pharmacol. 90(3) , 288-96, (2014)

Inhibition of 17α-hydroxylase/17,20-lyase (CYP17), which dictates the proceeding of androgen biosynthesis, is recommended as an effective treatment for androgen-dependent diseases. However, androgen depletion by selective CYP17 inhibition is accompanied with ...

Green synthesis of bacterial gold nanoparticles conjugated to resveratrol as delivery vehicles.

Colloids Surf. B Biointerfaces 123 , 311-7, (2014)

Bio-directed synthesis of metal nanoparticles is gaining importance in view of their biocompatibility, low toxicity and eco-friendly characteristics. The present study describes the application of resveratrol conjugated gold nanoparticles as effective deliver...

Mechanism of Dose-Dependent Regulation of UBE1L by Polyphenols in Human Bronchial Epithelial Cells.

J. Cell. Biochem. 116 , 1553-62, (2015)

Ubiquitin activating enzyme E1-like (UBE1L) is the activating enzyme for ISG15ylation (ISG15, interferon stimulated gene 15). UBE1L is thought to be a candidate tumor suppressor gene and has positive activity against stress responses such as viral infections....

ELF-MF attenuates quercetin-induced apoptosis in K562 cells through modulating the expression of Bcl-2 family proteins.

Mol. Cell Biochem. 397(1-2) , 33-43, (2014)

This study investigated the effects of sinusoidal ELF-MF (1 mT; 50 Hz) on the apoptosis induced by four different compounds, namely vinblastine, etoposide, quercetin, and resveratrol, in human K562 chronic myeloid leukemia cells. The exposure to ELF-MF did no...

Antimicrobial mechanism of resveratrol-trans-dihydrodimer produced from peroxidase-catalyzed oxidation of resveratrol.

Biotechnol. Bioeng. 112 , 2417-28, (2015)

Plant polyphenols are known to have varying antimicrobial potencies, including direct antibacterial activity, synergism with antibiotics and suppression of bacterial virulence. We performed the in vitro oligomerization of resveratrol catalyzed by soybean pero...

Anti-apoptotic and Beneficial Metabolic Activities of Resveratrol in Type II Gaucher Disease.

Biol. Pharm. Bull. 38 , 913-8, (2015)

Gaucher disease (GD) is one of the most common lysosomal storage disorders and is caused by an inherited deficiency in glucocerebrosidase. Resveratrol is a phytoalexin that has many beneficial activities, including anti-oxidant, anti-apoptotic, and neuroprote...

Resveratrol attenuates HMGB1 signaling and inflammation in house dust mite-induced atopic dermatitis in mice.

Int. Immunopharmacol. 23(2) , 617-23, (2015)

Resveratrol is a polyphenol abundantly found in red grape skin and is effective against antiaging and anti-inflammation associated with immune responses. In this study, we have investigated the effect of resveratrol on skin lesion, high mobility group box (HM...

Differential contribution of ROS to resveratrol-induced cell death and loss of self-renewal capacity of ovarian cancer stem cells.

Anticancer Res. 35(1) , 85-96, (2015)

Cancer stem cells (CSCs) are considered to contribute to the poor prognosis of ovarian cancer as a major cause of fatal recurrence. Identification of effective measures to eliminate ovarian CSCs through induction of cell death and/or loss of self-renewal capa...