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| 中文名 | 美登醇 |
|---|---|
| 英文名 | maytansinol |
| 中文别名 | 安丝菌素 P0 |
| 英文别名 |
4,24-Dioxa-9,22-diazatetracyclo[19.3.1.1.0]hexacosa-10,12,14(26),16,18-pentaene-8,23-dione, 11-chloro-6,21-dihydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-, (1S,2R,3S,5S,6S,16E,18E,20R,21S) 
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Ansamitocin P0 O3-de-(N-acetyl-N-methyl-L-alanyl)-maytansine (3E,5E,7R,84S)-14-chloro-10t,11c-epoxy-84,12c-dihydroxy-15,7r-dimethoxy-3,9c,11t,15-tetramethyl-(84r'H,86c'H)-15-aza-1(1,3)-benzena-8(4,6)-[1,3]oxazinana-cyclopentadecaphane-3,5-diene-82,14-dione (1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-Chloro-6,21-dihydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1.0]hexacosa-10(26),11,13,16,18-pentaene-8,23-dione Maytansinol (7) |
| 描述 | Maytansinol抑制微管组装且诱导微管解, 与辐射联用, 用于果蝇和人类癌细胞。 |
|---|---|
| 相关类别 | |
| 参考文献 |
| 密度 | 1.4±0.1 g/cm3 |
|---|---|
| 沸点 | 835.8±65.0 °C at 760 mmHg |
| 熔点 | >153C (dec.) |
| 分子式 | C28H37ClN2O8 |
| 分子量 | 565.055 |
| 闪点 | 459.3±34.3 °C |
| 精确质量 | 564.223816 |
| PSA | 130.09000 |
| LogP | 3.73 |
| 蒸汽压 | 0.0±3.2 mmHg at 25°C |
| 折射率 | 1.607 |
| 储存条件 | 2-8℃，惰性气体氛围 |
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~%
57103-68-1 |
| 文献：Journal of medicinal chemistry, , vol. 21, # 1 p. 31 - 37 |
|
~%
57103-68-1 |
| 文献：Journal of the American Chemical Society, , vol. 102, # 21 p. 6613 - 6615 |
|
~%
57103-68-1 |
| 文献：Journal of the American Chemical Society, , vol. 102, # 21 p. 6613 - 6615 |
|
~%
57103-68-1 |
| 文献：Journal of the American Chemical Society, , vol. 102, # 21 p. 6613 - 6615 |
|
~%
57103-68-1 |
| 文献：Journal of the American Chemical Society, , vol. 102, # 21 p. 6613 - 6615 |
|
~%
57103-68-1 |
| 文献：Journal of the American Chemical Society, , vol. 102, # 21 p. 6613 - 6615 |
|
~%
57103-68-1 |
| 文献：Tetrahedron, , vol. 35, p. 1079 - 1085 |
|
~%
57103-68-1 |
| 文献：Journal of the American Chemical Society, , vol. 102, # 21 p. 6613 - 6615 |
