决奈达隆

• 常用名: 决奈达隆
• 英文名: Dronedarone
• CAS号: 141626-36-0
• 分子量: 556.756
• 密度: 1.1±0.1 g/cm3
• 沸点: 683.9±65.0 °C at 760 mmHg
• 分子式: C₃₁H₄₄N₂O₅S
• 熔点: N/A
• 闪点: 367.4±34.3 °C

决奈达隆用途

Dronedarone(Multaq)可作用于阵发性和持续性房颤或房扑。

决奈达隆名称

• 中文名: 决奈达隆
• 英文名: dronedarone

决奈达隆生物活性

• 描述: Dronedarone(Multaq)可作用于阵发性和持续性房颤或房扑。
• 相关类别:
  信号通路 >> 自噬 >> 自噬
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 由mAChR
  信号通路 >> 神经信号通路 >> mAChR
  研究领域 >> 心血管疾病
• 参考文献:

  [1]. Piccinni C, et al.Trends in antiarrhythmic drug use after marketing authorization of dronedarone: comparison between Emilia Romagna (Italy) and Sweden.Eur J Clin Pharmacol. 2012 Sep 1.

  [2]. Benaim G, et al.The emerging role of amiodarone and dronedarone in Chagas disease.Nat Rev Cardiol. 2012 Aug 7.

  [3]. Rosman J, et al. Possible Proarrhythmia with Dronedarone.J Cardiovasc Electrophysiol. 2012 Jul 19.

  [4]. Kao DP, et al. Proarrhythmic Potential of Dronedarone: Emerging Evidence from Spontaneous Adverse Event Reporting.Pharmacotherapy. 2012 Jun 28.

  [5]. Manakshe G, Rao BH.Dronedarone-current status in management of atrial fibrillation.Indian Heart J. 2012 Mar-Apr;64(2):182-6. Epub 2012 Apr 28.

决奈达隆物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 683.9±65.0 °C at 760 mmHg
• 分子式: C₃₁H₄₄N₂O₅S
• 分子量: 556.756
• 闪点: 367.4±34.3 °C
• 精确质量: 556.297119
• PSA: 97.23000
• LogP: 7.58
• InChIKey: ZQTNQVWKHCQYLQ-UHFFFAOYSA-N
• SMILES: CCCCc1oc2ccc(NS(C)(=O)=O)cc2c1C(=O)c1ccc(OCCCN(CCCC)CCCC)cc1
• 蒸汽压: 0.0±2.1 mmHg at 25°C
• 折射率: 1.564
• 储存条件: -20°C

决奈达隆安全信息

• 危害码 (欧洲): Xi
• 海关编码: 3004909090

决奈达隆海关

• 海关编码: 3004909090

决奈达隆靶点实验

查看更多实验

实验名称：Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression 来源：NCGC External Id：SNCA-p-activity-luciferase

实验名称：Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu... 来源：824 External Id：CYP273

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-keats_OPM1-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-OC1MY5-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-KMS_34-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-keats_L363-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-keats_OCIMY7-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-MM1R-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-mm1s-m4-1

实验名称：Quantitative High-Throughput drug screen in 47 multiple myeloma cell lines against th... 来源：NCGC 靶标：N/A External Id：s-my-KMS-28PE-m4-1

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决奈达隆英文别名

• UNII-JQZ1L091Y2
• N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-1-benzofuran-5-yl]methanesulfonamide
• Multaq
• N-(2-Butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)-1-benzofuran-5-yl)methanesulfonamide
• Dronedarone
• N-(2-Butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl)methanesulfonamide