原水仙碱结构式
|
常用名 | 原水仙碱 | 英文名 | Colchiceine |
|---|---|---|---|---|
| CAS号 | 477-27-0 | 分子量 | 385.41000 | |
| 密度 | 1.31g/cm3 | 沸点 | 731.5ºC at 760mmHg | |
| 分子式 | C21H23NO6 | 熔点 | 172-174ºC | |
| MSDS | N/A | 闪点 | 396.2ºC |
| 中文名 | 原秋水仙碱 |
|---|---|
| 英文名 | Colchiceine |
| 中文别名 | 10-去甲秋水仙碱 | 原秋水仙鹼 |
| 英文别名 | 更多 |
| 密度 | 1.31g/cm3 |
|---|---|
| 沸点 | 731.5ºC at 760mmHg |
| 熔点 | 172-174ºC |
| 分子式 | C21H23NO6 |
| 分子量 | 385.41000 |
| 闪点 | 396.2ºC |
| 精确质量 | 385.15300 |
| PSA | 94.09000 |
| LogP | 2.95950 |
| InChIKey | PRGILOMAMBLWNG-HNNXBMFYSA-N |
| SMILES | COc1cc2c(c(OC)c1OC)-c1ccc(O)c(=O)cc1C(NC(C)=O)CC2 |
| 蒸汽压 | 1.83E-22mmHg at 25°C |
| 折射率 | 1.61 |
| 储存条件 | 库房通风低温干燥 |
| 危害码 (欧洲) | T+ |
|---|---|
| 海关编码 | 2924299090 |
|
~%
原水仙碱 477-27-0 |
| 文献:Roesner, Manfred; Capraro, Hans-Georg; Jacobson, Arthur E.; Atwell, Louise; Brossi, Arnold; et al. Journal of Medicinal Chemistry, 1981 , vol. 24, # 3 p. 257 - 261 |
|
~%
原水仙碱 477-27-0 |
| 文献:Corrodi; Hardegger Helvetica Chimica Acta, 1957 , vol. 40, p. 193,198, 199 |
|
~%
原水仙碱 477-27-0 |
| 文献:Dumont; Brossi; Silverton Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2515 - 2521 |
|
~%
原水仙碱 477-27-0 |
| 文献:Dumont; Brossi; Silverton Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2515 - 2521 |
|
~%
原水仙碱 477-27-0 |
| 文献:Dumont; Brossi; Silverton Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2515 - 2521 |
|
~%
原水仙碱 477-27-0 |
| 文献:Dumont; Brossi; Silverton Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2515 - 2521 |
|
~%
原水仙碱 477-27-0 |
| 文献:Dumont; Brossi; Silverton Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2515 - 2521 |
|
~%
原水仙碱 477-27-0 |
| 文献:Dumont; Brossi; Silverton Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2515 - 2521 |
|
~%
原水仙碱 477-27-0 |
| 文献:Corrodi; Hardegger Helvetica Chimica Acta, 1957 , vol. 40, p. 193,198, 199 |
| 原水仙碱上游产品 10 | |
|---|---|
| 原水仙碱下游产品 10 | |
| 海关编码 | 2924299090 |
|---|---|
| 中文概述 | 2924299090. 其他环酰胺(包括环氨基甲酸酯)(包括其衍生物以及他们的盐). 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0% |
| 申报要素 | 品名, 成分含量, 用途, 包装 |
| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
|
实验名称:Luminescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id:OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
|
|
实验名称:QFRET-based biochemical primary high throughput screening assay to identify exosite i...
来源:The Scripps Research Institute Molecular Screening Center
靶标:disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id:ADAM17_INH_QFRET_1536_1X%INH PRUN
|
|
实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
|
|
实验名称:uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
来源:Burnham Center for Chemical Genomics
靶标:N/A
External Id:BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
|
|
实验名称:Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
来源:Broad Institute
靶标:FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id:2147-01_Inhibitor_SinglePoint_HTS_Activity
|
|
实验名称:Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
来源:Broad Institute
靶标:N/A
External Id:Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
|
|
实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify pos...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
|
|
实验名称:Fluorescence polarization-based biochemical high throughput primary assay to identify...
来源:The Scripps Research Institute Molecular Screening Center
靶标:RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id:SIAE_INH_FP_1536_1X%INH PRUN
|
|
实验名称:Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 3 (E...
来源:NCGC
External Id:epac1-activator-v
|
|
实验名称:Absorbance-based primary biochemical high throughput screening assay to identify acti...
来源:The Scripps Research Institute Molecular Screening Center
靶标:caspase-3 preproprotein [Homo sapiens]
External Id:PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN
|
| colchiceine |