7-木糖甙-10-脱乙酰基紫杉醇

更新时间：2024-01-04 21:46:47

7-木糖甙-10-脱乙酰基紫杉醇结构式	常用名	7-木糖甙-10-脱乙酰基紫杉醇	英文名	10-Deacetyl-7-xylosyl paclitaxel
	CAS号	90332-63-1	分子量	943.984
	密度	1.5±0.1 g/cm3	沸点	1068.4±65.0 °C at 760 mmHg
	分子式	C₅₀H₅₇NO₁₇	熔点	N/A
	MSDS	N/A	闪点	599.9±34.3 °C

7-木糖甙-10-脱乙酰基紫杉醇用途

10-Deacetyl-7-xylosyl paclitaxel是Paclitaxel的衍生物,相比Paclitaxel,具有更好的药学活性和水溶性。

中文名	7-木糖甙-10-脱乙酰基紫杉醇
英文名	7-Xylosyl-10-deacetyltaxol
中文别名	7-木糖-10-去乙酰基紫杉醇 \| 7-木糖苷-10-脱乙酰基紫杉醇
英文别名	更多

描述	10-Deacetyl-7-xylosyl paclitaxel是Paclitaxel的衍生物,相比Paclitaxel,具有更好的药学活性和水溶性。
相关类别	信号通路 >> 抗体- 药物偶联物 >> ADC细胞毒素信号通路 >> 细胞周期/DNA损伤 >> 微管/微管蛋白信号通路 >> 细胞骨架 >> 微管/微管蛋白研究领域 >> 癌症
参考文献	[1]. Jiang S, et al. Activation of the mitochondria-driven pathway of apoptosis in human PC-3 prostate cancer cells by a novel hydrophilic paclitaxel derivative, 7-xylosyl-10-deacetylpaclitaxel. Int J Oncol. 2008 Jul;33(1):103-11.

密度	1.5±0.1 g/cm3
沸点	1068.4±65.0 °C at 760 mmHg
分子式	C₅₀H₅₇NO₁₇
分子量	943.984
闪点	599.9±34.3 °C
精确质量	943.362671
PSA	274.14000
LogP	7.18
蒸汽压	0.0±0.3 mmHg at 25°C
折射率	1.660
储存条件	2-8℃

Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-t etramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-

(2α,3β,5β,7β,10β,13α)-4-Acetoxy-13-{[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy}-1,10-dihydroxy-9-oxo-7-(β-D-xylopyranosyloxy)-5,20-epoxytax-11-en-2-yl benzoate

(2α,5β,7β,10β,13α)-4-Acetoxy-13-{[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy}-1,10-dihydroxy-9-oxo-7-(β-D-xylopyranosyloxy)-5,20-epoxytax-11-en-2-yl benzoate

Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aS,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-t etramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-

10-Deacetyl-7-xylosyl paclitaxel