四环素亚甲赖氨酸

• 常用名: 四环素亚甲赖氨酸
• 英文名: Lymecycline
• CAS号: 992-21-2
• 分子量: 602.63
• 密度: 1.53
• 沸点: 840.5ºC at 760 mmHg
• 分子式: C₂₉H₃₈N₄O₁₀
• 熔点: 192.5°C
• 闪点: 462.1ºC

四环素亚甲赖氨酸用途

Lymecycline 是四环素衍生物,具有广谱的抗菌活性,同时具有抗炎活性。

四环素亚甲赖氨酸名称

• 中文名: 赖甲环素
• 英文名: lymecycline
• 中文别名: 四环素亚甲赖氨酸

四环素亚甲赖氨酸生物活性

• 描述: Lymecycline 是四环素衍生物,具有广谱的抗菌活性,同时具有抗炎活性。
• 相关类别:
  研究领域 >> 感染
  研究领域 >> 炎症/免疫
  信号通路 >> 抗感染 >> 细菌
• 靶点实验:

  Bacterial[1]

• 体外研究: 利美环素是一种四环素衍生物,具有广谱抗菌活性,可干扰核糖体水平的原核蛋白合成。利美环素还具有抗炎特性[1]。
• 参考文献:

  [1]. Rempe S, et al. Tetracyclines and pulmonary inflammation. Endocr Metab Immune Disord Drug Targets. 2007 Dec;7(4):232-6.

四环素亚甲赖氨酸物理化学性质

• 密度: 1.53
• 沸点: 840.5ºC at 760 mmHg
• 熔点: 192.5°C
• 分子式: C₂₉H₃₈N₄O₁₀
• 分子量: 602.63
• 闪点: 462.1ºC
• 精确质量: 602.25900
• PSA: 242.98000
• LogP: 1.02790
• 折射率: 1.693
• 水溶解性: Very soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.

四环素亚甲赖氨酸毒性和生态

四环素亚甲赖氨酸靶点实验

查看更多实验

实验名称：Compound was evaluated for inhibition of rat Gabra1 in an in vitro assay with cellula... 来源：ChEMBL 靶标：Gamma-aminobutyric acid receptor subunit alpha-1 External Id：CHEMBL5291801

实验名称：Binding affinity towards rat Gabra1 in an in vitro assay with cellular components mea... 来源：ChEMBL 靶标：Gamma-aminobutyric acid receptor subunit alpha-1 External Id：CHEMBL5291798

实验名称：Binding affinity towards human ESR1 in an in vitro cell free assay (NIBR assay) measu... 来源：ChEMBL 靶标：Estrogen receptor External Id：CHEMBL5291791

实验名称：Binding affinity towards human HRH3 in an in vitro assay with cellular components mea... 来源：ChEMBL 靶标：Histamine H3 receptor External Id：CHEMBL5291921

实验名称：Choleostatic liver toxicity, either proven histopathologically or where the ratio of ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3137727

实验名称：Severe hepatitis, defined as possibly life-threatening liver failure or through clini... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3137728

实验名称：Chronic liver disease either proven histopathologically, or through a chonic elevatio... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3137729

实验名称：Cirrhosis, proven histopathologically. Value is number of references indexed. [column... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3137730

实验名称：Granulomatous liver disease, proven histopathologically. Value is number of reference... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3137731

实验名称：Liver damage due to vascular disease: peliosis hepatitis, hepatic veno-occlusive dise... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3137732

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四环素亚甲赖氨酸英文别名

• limecycline
• [(1r,7ar)-1-hydroxy-2,3,5,7a-tetrahydro-1h-pyrrolizin-7-yl]methyl(2r,3s)-2,3-dihydroxy-2-isopropylbutanoate
• 2,3-Dihydroxy-2-(1-methylethyl)-butanoic acid (2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl) methyl ester
• lycopsamine
• (+)-Indicine