4-Chlorobenzaldehyde

4-Chlorobenzaldehyde Structure
4-Chlorobenzaldehyde structure
Common Name 4-Chlorobenzaldehyde
CAS Number 104-88-1 Molecular Weight 140.567
Density 1.2±0.1 g/cm3 Boiling Point 213.7±13.0 °C at 760 mmHg
Molecular Formula C7H5ClO Melting Point 46 °C
MSDS Chinese USA Flash Point 87.8±0.0 °C
Symbol GHS07
GHS07
Signal Word Warning

A universal quantitative ¹H nuclear magnetic resonance (qNMR) method for assessing the purity of dammarane-type ginsenosides.

Phytochem. Anal. 26(1) , 8-14, (2014)

Quantitative (1)H-NMR (qNMR) is a well-established method for quantitative analysis and purity tests. Applications have been reported in many areas, such as natural products, foods and beverages, metabolites, pharmaceuticals and agriculture. The characteristi...

Acetalization allows the photoheterolysis of the Ar-Cl bond in chlorobenzaldehydes and chloroacetophenones.

J. Org. Chem. 77(20) , 9094-101, (2012)

The nonaccessibility of phenyl cations by irradiation of electron-poor aryl chlorides was circumvented by transforming the carbonyl group of aromatic ketones or aldehydes into the corresponding 1,3-dioxolanes and the carboxyl group of benzoate ester into an o...

Growth of Thin, Anisotropic, π-Conjugated Molecular Films by Stepwise "Click" Assembly of Molecular Building Blocks: Characterizing Reaction Yield, Surface Coverage, and Film Thickness versus Addition Step Number.

J. Am. Chem. Soc. 137 , 8819-28, (2015)

We report the systematic characterization of anisotropic, π-conjugated oligophenyleneimine (OPI) films synthesized using stepwise imine condensation, or "click" chemistry. Film synthesis began with a self-assembled monolayer (SAM) of 4-formylthiophenol or 4-a...

Synthesis and receptor binding assay of indolin-2-one derivatives as dopamine D4 receptor ligands.

Pharmazie 70 , 511-4, (2015)

Five indolin-2-one derivatives bearing piperazinylbutyl side chains attached to the amide nitrogen were synthesized from 2-indolinone. 1-(4-Bromobutyl)-indolin-2-one was reacted with 1-piperazinecarboxaldehyde to form 1-(4-(4-formyl-1-piperazinyl)butyl)indoli...

Experimental and theoretical studies of the products of addition-elimination reactions between benzil dihydrazone and three isomeric chlorobenzaldehydes.

Acta Crystallogr. C Struct. Chem. 71 , 554-63, (2015)

A series of mono- and di-Schiff bases formed between benzil dihydrazone {BDH; systematic name: (1Z)-[(2E)-2-hydrazinylidene-1,2-diphenylethylidene]hydrazine} and three isomeric chlorobenzaldehydes were designed and synthesized to be used as model compounds to...

(E)-3-tert-butyl-4-(4-chlorobenzyl)-N-(4-chlorobenzylidene)-1-phenyl-1H-pyrazol-5-amine: sheets built from π-stacked hydrogen-bonded dimers.

Acta Crystallogr. C 69(Pt 9) , 1039-42, (2013)

The title compound, C27H25Cl2N3, is an unexpected but high-yield product from the microwave-mediated reaction between 3-tert-butyl-N-4-chlorobenzyl-1-phenyl-1H-pyrazol-5-amine and 4-chlorobenzaldehyde. Inversion-related pairs of molecules are linked by C-H···...

First Novozym 435 lipase-catalyzed Morita-Baylis-Hillman reaction in the presence of amides.

Enzyme Microb. Technol. 84 , 32-40, (2016)

The first Novozym 435 lipase-catalyzed Morita-Baylis-Hillman (MBH) reaction with amides as co-catalyst was realized. Results showed that neither Novozym 435 nor amide can independently catalyze the reaction. This co-catalytic system that used a catalytic amou...

[Experimental substantiation of an approximate safe level of p-chlorobenzaldehyde in the air of the work area].

Gig. Tr. Prof. Zabol. (2) , 50-1, (1987)

An efficient, multicomponent approach for solvent-free synthesis of 2-amino-4H-chromene scaffold.

Mol. Divers. 14(3) , 473-7, (2010)

Solvent-free one-pot synthesis of 2-amino-4H-chromene scaffold is described in a very simple, efficient, and environmentally benign method using sodium carbonate as a cheap and non-toxic catalyst with up to excellent yields.

Toward the development of chemoprevention agents. Part 1: Design, synthesis, and anti-inflammatory activities of a new class of 2,5-disubstituted-dioxacycloalkanes.

Bioorg. Med. Chem. 15 , 4775-99, (2007)

A new class of 2,5-disubstituted-dioxacycloalkanes were designed and synthesized via stereoselective synthetic method as cancer chemoprevention agents. The anti-inflammatory activities of these compounds were tested using the xylene-induced mouse ear edema mo...