Methylene Blue
Methylene Blue structure
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Common Name | Methylene Blue | ||
|---|---|---|---|---|
| CAS Number | 61-73-4 | Molecular Weight | 319.85200 | |
| Density | 1.0 g/mL at 20 °C | Boiling Point | N/A | |
| Molecular Formula | C16H18ClN3S | Melting Point | 190 °C (dec.)(lit.) | |
| MSDS | Chinese | Flash Point | 45 °C | |
| Symbol |
GHS02 |
Signal Word | Warning | |
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Organization of pontine reticulospinal inputs to motoneurons controlling axial and limb muscles in the neonatal mouse.
J. Neurophysiol. 112(7) , 1628-43, (2014) Using optical recording of synaptically mediated calcium transients and selective spinal lesions, we investigated the pattern of activation of spinal motoneurons (MNs) by the pontine reticulospinal projection in isolated brain stem-spinal cord preparations fr... |
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High-throughput fluorescence-based screening assays for tryptophan-catabolizing enzymes.
J. Biomol. Screen. 19(9) , 1266-74, (2014) Indoleamine 2,3-dioxygenase (IDO1) and tryptophan 2,3-dioxygenase (TDO) are two structurally different enzymes that have a different tissue distribution and physiological roles, but both catalyze the conversion of tryptophan to N-formylkynurenine (NFK). IDO1 ... |
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Cytochrome C reacts with cholesterol hydroperoxides to produce lipid- and protein-derived radicals.
Biochemistry 54 , 2841-50, (2015) Lipid peroxidation is a well-known process that has been implicated in many diseases. Recent evidence has shown that mitochondrial cholesterol levels are increased under specific conditions, making it an important target for peroxidation inside the mitochondr... |
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Minimal detection of nuclear mutations in XP-V and normal cells treated with oxidative stress inducing agents.
J. Biochem. Mol. Toxicol. 28(12) , 568-77, (2014) Elevated levels of reactive oxygen species (ROS) can be induced by exposure to various chemicals and radiation. One type of damage in DNA produced by ROS is modification of guanine to 7,8-dihydro-8-oxoguanine (8-oxoG). This particular alteration to the chemis... |
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In Vitro Protective Effect and Antioxidant Mechanism of Resveratrol Induced by Dapsone Hydroxylamine in Human Cells.
PLoS ONE 10 , e0134768, (2015) Dapsone (DDS) hydroxylamine metabolites cause oxidative stress- linked adverse effects in patients, such as methemoglobin formation and DNA damage. This study evaluated the ameliorating effect of the antioxidant resveratrol (RSV) on DDS hydroxylamine (DDS-NHO... |
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Four different synthetic peptides of proteolipid protein induce a distinct antibody response in MP4-induced experimental autoimmune encephalomyelitis.
Clin. Immunol. 159 , 93-106, (2015) Here we studied the autoantibody specificity elicited by proteolipid protein (PLP) in MP4-induced experimental autoimmune encephalomyelitis, a mouse model of multiple sclerosis (MS). In C57BL/6 (B6) mice, antibodies were induced by immunization with one of th... |
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Pseudomonas aeruginosa Biofilm Formation and Persistence, along with the Production of Quorum Sensing-Dependent Virulence Factors, Are Disrupted by a Triterpenoid Coumarate Ester Isolated from Dalbergia trichocarpa, a Tropical Legume.
PLoS ONE 10 , e0132791, (2015) Recently, extracts of Dalbergia trichocarpa bark have been shown to disrupt P. aeruginosa PAO1 quorum sensing (QS) mechanisms, which are key regulators of virulence factor expression and implicated in biofilm formation. One of the active compounds has been is... |
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Loss of CARD9-mediated innate activation attenuates severe influenza pneumonia without compromising host viral immunity.
Sci. Rep. 5 , 17577, (2015) Influenza virus (IFV) infection is a common cause of severe viral pneumonia associated with acute respiratory distress syndrome (ARDS), which is difficult to control with general immunosuppressive therapy including corticosteroids due to the unfavorable effec... |
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On the Origin and Underappreciated Effects of Ion Doping in Silica.
Small 11 , 4351-65, (2015) The origin of selectivity in the hollowing of silica nanoparticles is investigated to further understand silica. It is realized that, during the synthesis, the silica precursors are essentially ion-paired polyelectrolytes, whose nucleation depends on the conc... |
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Natural Plasmodium infection in neotropical primates in the island of São Luís, state of Maranhão, Brazil.
Rev. Bras. Parasitol. Vet. 24 , 122-8, (2015) The states that make up the Legal Amazon Region, which include the state of Maranhão, account for 99% of registered cases of human malaria in Brazil. It is also believed that transmission of malaria from nonhuman primates (NHP) to humans occurs in this region... |