Beta-Sitosterol

Beta-Sitosterol Structure
Beta-Sitosterol structure
Common Name Beta-Sitosterol
CAS Number 83-46-5 Molecular Weight 414.707
Density 1.0±0.1 g/cm3 Boiling Point 501.9±19.0 °C at 760 mmHg
Molecular Formula C29H50O Melting Point 139-142 ºC
MSDS Chinese USA Flash Point 220.4±13.7 °C
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.

Chem. Res. Toxicol. 23 , 171-83, (2010)

Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental drug discovery projects toward safer medicines. In this st...

Nutritional evaluation and health promoting activities of nuts and seeds cultivated in Greece.

Int. J. Food Sci. Nutr. 64(6) , 757-67, (2013)

Available data suggest that genetic as well as environmental factors may influence nuts and seeds nutrients content. In this context nuts and seeds cultivated in Greece were studied. Macronutrients content was in agreement with that from other areas. Total ph...

Elevated serum squalene and cholesterol synthesis markers in pregnant obese women with gestational diabetes mellitus.

J. Lipid Res. 55(12) , 2644-54, (2014)

We examined serum cholesterol synthesis and absorption markers and their association with neonatal birth weight in obese pregnancies affected by gestational diabetes mellitus (GDM). Pregnant women at risk for GDM (BMI >30 kg/m²) were enrolled from maternity c...

Antidiabetic property of Symplocos cochinchinensis is mediated by inhibition of alpha glucosidase and enhanced insulin sensitivity.

PLoS ONE 9(9) , e105829, (2014)

The study is designed to find out the biochemical basis of antidiabetic property of Symplocos cochinchinensis (SC), the main ingredient of 'Nisakathakadi' an Ayurvedic decoction for diabetes. Since diabetes is a multifactorial disease, ethanolic extract of th...

On-line liquid chromatography-gas chromatography: A novel approach for the analysis of phytosterol oxidation products in enriched foods.

J. Chromatogr. A. 1396 , 98-108, (2015)

A novel methodology for the automated qualitative and quantitative determination of phytosterol oxidation products in enriched foods via on-line liquid chromatography-gas chromatography (LC-GC) was established. The approach is based on the LC pre-separation o...

Tylosema esculentum extractives and their bioactivity.

Bioorg. Med. Chem. 19 , 5225-30, (2011)

The investigation of Tylosema esculentum (Morama) husks, cotyledons, and tuber yielded griffonilide 2, compound 1, griffonin 3, gallic acid 4, protocatechuic acid 5, β-sitosterol 6, behenic acid 7, oleic acid 8, sucrose 9, 2-O-ethyl-α-D-glucopyranoside 10, ka...

Changes in the triterpenoid content of cuticular waxes during fruit ripening of eight grape (Vitis vinifera) cultivars grown in the Upper Rhine Valley.

J. Agric. Food Chem. 62(32) , 7998-8007, (2014)

Triterpenoids present in grape cuticular waxes are of interest due to their potential role in protection against biotic stresses, their impact on the mechanical toughness of the fruit surface, and the potential industrial application of these biologically act...

The effect of traditional stir-frying process on hydrophilic and lipophilic antioxidant capacities of pine nut kernels.

Int. J. Food Sci. Nutr. 66 , 873-80, (2015)

The effect of traditional stir-frying process at different heating temperatures (50-150 °C) and time periods (5-20 min) on hydrophilic part (total and individual phenolics), lipophilic part (tocopherol and phytosterol compounds) and their corresponding antiox...

Influence of ultra-high-pressure homogenization treatment on the phytosterols, tocopherols, and polyamines of almond beverage.

J. Agric. Food Chem. 62(39) , 9539-43, (2014)

Ultra-high-pressure homogenization (UHPH) is an emerging technology based on the dynamic application of high pressure to obtain safe and high-quality liquid foods. The effect of six UHPH treatments at 200 and 300 MPa with different inlet temperatures (T(in)) ...

Ezetimibe reduces plant sterol accumulation and favorably increases platelet count in sitosterolemia.

J. Pediatr. 166(1) , 125-31, (2015)

To assess if ezetimibe (EZE), a sterol-absorption inhibitor, improves platelet (PLT) count and size relative to its effect on plasma plant sterol (PS) in patients with sitosterolemia (STSL).Patients with STSL (5 males, 3 females, 16-56 years of age) receiving...