α-Hemolysin (Staphylococcus aureus)
α-Hemolysin (Staphylococcus aureus) structure
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Common Name | α-Hemolysin (Staphylococcus aureus) | ||
|---|---|---|---|---|
| CAS Number | 94716-94-6 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Staphylococcal alpha toxin--recent advances.
Toxicon 26 , 55-65, (1988) The elucidation of the amino acid sequence of alpha toxin in 1984 has greatly promoted our understanding of the basic biochemistry and interaction of this toxin with membranes. These aspects are discussed and the concept of alpha toxin as a channel forming pr... |
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Adaptation to benzalkonium chloride and ciprofloxacin affects biofilm formation potential, efflux pump and haemolysin activity of Escherichia coli of dairy origin.
J. Dairy Res. 79(4) , 383-9, (2012) The present study investigates the effect of adaptive resistance to ciprofloxacin (Cip) and benzalkonium chloride (BC) on biofilm formation potential (BFP), efflux pump activity (EPA) and haemolysin activity of Escherichia coli isolates of dairy origin. All t... |
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A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome.
J. Histochem. Cytochem. 183 , 3942-8, (2009) The mechanism by which bacterial pathogens activate caspase-1 via Nlrp3 remains poorly understood. In this study, we show that the ability of Staphylococcus aureus, a leading cause of infection in humans, to activate caspase-1 and induce IL-1beta secretion re... |
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Annular protofibrils are a structurally and functionally distinct type of amyloid oligomer.
J. Bacteriol. 284 , 4230-7, (2009) Amyloid oligomers are believed to play causal roles in several types of amyloid-related neurodegenerative diseases. Several different types of amyloid oligomers have been reported that differ in morphology, size, or toxicity, raising the question of the patho... |
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Differential dissociation of G protein heterotrimers.
J. Phys. Chem. 586 , 3325-35, (2008) Signalling by heterotrimeric G proteins is often isoform-specific, meaning certain effectors are regulated exclusively by one family of heterotrimers. For example, in excitable cells inwardly rectifying potassium (GIRK) channels are activated by G betagamma d... |
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Staphylococcus aureus alpha-toxin activates phospholipases and induces a Ca2+ influx in PC12 cells.
Cell. Signal. 1 , 387-393, (1989) Staphylococcal alpha-toxin at subcytotoxic concentrations stimulated phosphatidylinositol turnover and arachidonic acid release in undifferentiated cultures of pheochromocytoma PC12 cells. Stimulation of phospholipase A2 but not C was dependent on extracellul... |
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In vivo mapping of a protective linear neutralizing epitope at the N-terminus of alpha hemolysin from Staphylococcus aureus.
Mol. Immunol. 60(1) , 62-71, (2014) Staphylococcus aureus is responsible for a large and diverse burden of human disease associated with significant morbidity and mortality. The dynamic challenge of this pathogen is exemplified by the emergence of highly virulent community-associated methicilli... |