Sal003
Sal003 structure
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Common Name | Sal003 | ||
|---|---|---|---|---|
| CAS Number | 1164470-53-4 | Molecular Weight | 463.208 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C18H15Cl4N3OS | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS09 |
Signal Word | Warning | |
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Translational Control of Long-Lasting Synaptic Plasticity and Memory
Neuron 61(1) , 10-26, (2009) Long-lasting forms of synaptic plasticity and memory are dependent on new protein synthesis. Recent advances obtained from genetic, physiological, pharmacological, and biochemical studies provide strong evidence that translational control plays a key role in ... |
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Regulation of subtilase cytotoxin-induced cell death by an RNA-dependent protein kinase-like endoplasmic reticulum kinase-dependent proteasome pathway in HeLa cells.
Infect. Immun. 80(5) , 1803-14, (2012) Shiga-toxigenic Escherichia coli (STEC) produces subtilase cytotoxin (SubAB), which cleaves the molecular chaperone BiP in the endoplasmic reticulum (ER), leading to an ER stress response and then activation of apoptotic signaling pathways. Here, we show that... |
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Switching gears: translational mastery of transcription during memory formation.
Neuron 54(2) , 186-9, (2007) A critical molecular requirement underlying many forms of long-lasting synaptic plasticity and memory is the de novo synthesis of mRNAs and proteins. In a recent paper in Cell, Costa-Mattioli et al. present data from a pharmacogenetic study that places a key ... |
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HDAC pharmacological inhibition promotes cell death through the eIF2α kinases PKR and GCN2.
Aging (Albany. NY.) 2 , 669-77, (2010) Histone deacetylase inhibitors (HDACi) comprise a family of chemotherapeutic agents used in the clinic to treat cutaneous T-cell lymphoma and tested for the therapy of other malignancies. Previous reports have shown that eIF2α phosphorylation is induced upon ... |
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Phospho-eIF2α level is important for determining abilities of BACE1 reduction to rescue cholinergic neurodegeneration and memory defects in 5XFAD mice.
PLoS ONE 5 , e12974, (2010) β-Site APP-cleaving enzyme 1 (BACE1) initiates amyloid-β (Aβ) generation and thus represents a prime therapeutic target in treating Alzheimer's disease (AD). Notably, increasing evidence indicates that BACE1 levels become elevated in AD brains as disease prog... |
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Upregulation of the coagulation factor VII gene during glucose deprivation is mediated by activating transcription factor 4.
PLoS ONE 7 , e40994, (2012) Constitutive production of blood coagulation proteins by hepatocytes is necessary for hemostasis. Stressful conditions trigger adaptive cellular responses and delay processing of most proteins, potentially affecting plasma levels of proteins secreted exclusiv... |