Ethynodiol diacetate

Ethynodiol diacetate Structure
Ethynodiol diacetate structure
Common Name Ethynodiol diacetate
CAS Number 297-76-7 Molecular Weight 384.509
Density 1.1±0.1 g/cm3 Boiling Point 461.1±45.0 °C at 760 mmHg
Molecular Formula C24H32O4 Melting Point 128 - 131ºC
MSDS Chinese USA Flash Point 221.8±27.1 °C
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning

Suppressive effect of neonatal treatment with a phytoestrogen, coumestrol, on lordosis and estrous cycle in female rats.

Brain Res. Bull. 64(5) , 449-54, (2005)

The neural control systems for the ovulatory cycle and lordosis behavior are sexually differentiated by estrogen during the perinatal period in rats. In the present study, the effects of a single neonatal injection with the phytoestrogen, coumestrol, on femal...

New observations on endometrial physiology after transcervical injection of methylene blue dye.

Fertil. Steril. 82(6) , 1700-4, (2004)

We describe the in vivo features of endometrium stained with methylene blue dye and observed via microhysteroscopy, showing the patterns of endometrial glands and superficial cell changes during the midproliferative, periovulatory, and midluteal phases. These...

Membrane-initiated steroid signaling (MISS): genomic steroid action starts at the plasma membrane.

J. Steroid Biochem. Mol. Biol. 85(1) , 9-23, (2003)

Plasma membrane (PM) steroid recognition sites are thought to be responsible only for rapid, non-genomic responses without any link to the nuclear receptor-mediated genomic effects of steroids. We focused on a PM "glucocorticoid-importer" (GC-importer) that i...

Efficacy and safety of ethynodiol diacetate, 1 mg, with ethinyl estradiol, 35 micrograms, with an emphasis on contraceptive efficacy. A phase IV trial.

J. Reprod. Med. 36(4 Suppl) , 328-33, (1991)

A phase IV trial evaluated the efficacy and safety of a monophasic oral contraceptive formulation, ethynodiol diacetate, 1 mg, plus ethinyl estradiol, 35 micrograms (EDA 1 mg with EE 35 micrograms) (Demulen 1/35). Nine hundred eighty-three community-based obs...

Do AshSplit haemodialysis catheters provide better flow rates in the long term?

Ren. Fail. 29(6) , 721-9, (2007)

Recently, interventional radiologists have adopted an increasingly prominent role in the placement and management of hemodialysis catheters, as well as in the research and development of new and better catheters. The purpose of this study was to evaluate the ...

Incidence of ovarian cyst formation in women taking ethynodiol diacetate, 1 mg, with ethinyl estradiol, 35 micrograms.

J. Reprod. Med. 36(4 Suppl) , 345-9, (1991)

A total of 7,759 women were treated with ethynodiol diacetate, 1 mg, with ethinyl estradiol, 35 micrograms (EDA 1 mg with EE 35 micrograms) in a field study involving 983 obstetrician-gynecologists evaluating the incidence of ovarian cyst formation. Six thous...

Complexion changes in oral contraceptive users. Results from a phase IV multicenter trial evaluating the safety and efficacy of ethynodiol diacetate, 1 mg, with ethinyl estradiol, 35 micrograms.

J. Reprod. Med. 36(4 Suppl) , 340-4, (1991)

An open-label, phase IV, multicenter survey of obstetrician-gynecologists was conducted to evaluate the efficacy and safety of a low-dose monophasic oral contraceptive, ethynodiol diacetate, 1 mg, with ethinyl estradiol, 35 micrograms. Surveys from 983 commun...

Incidence of breakthrough bleeding during oral contraceptive therapy.

J. Reprod. Med. 36(4 Suppl) , 334-9, (1991)

A phase IV, open-label, multicenter survey of 983 obstetrician-gynecologists was conducted to evaluate the incidence of intermenstrual bleeding in 6,382 women receiving a low-dose monophasic oral contraceptive, ethynodiol diacetate, 1 mg, with ethinyl estradi...

Successful treatment of hirsutism in HAIR-AN syndrome using flutamide, spironolactone, and birth control therapy.

Arch. Dermatol. 133(4) , 431-3, (1997)

Contraceptive failure and the progestogen-only pill.

J. Fam. Plann. Reprod. Health Care 36(3) , 182, (2010)