Cyanamide
Cyanamide structure
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Common Name | Cyanamide | ||
|---|---|---|---|---|
| CAS Number | 420-04-2 | Molecular Weight | 42.040 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 258.5±0.0 °C at 760 mmHg | |
| Molecular Formula | CH2N2 | Melting Point | 45-46 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 1.2±22.6 °C | |
| Symbol |
GHS05, GHS06, GHS08 |
Signal Word | Danger | |
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Synthesis of novel phosphorylated guanidine derivatives from cyanamide and their anti-inflammatory activity.
Chem. Pharm. Bull. 61(1) , 25-32, (2013) A series of novel guanidine derivatives were synthesized in three steps and their anti-inflammatory activities in vitro and in vivo evaluated. 2-Aminopyridin-3-ol (1) was reacted with thiophosphoryl chloride (2) to give a monochloride (3). It was further reac... |
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Aldehyde dehydrogenase 2 partly mediates hypotensive effect of nitrite on L-NAME-induced hypertension in normoxic rat.
Clin. Exp. Hypertens. 36(6) , 410-8, (2014) Nitrite has become a topic of interest in the field of medical research because of its potential therapeutic role as an alternative source of nitric oxide (NO). While the bioconversion of nitrite to NO occurs via either nonenzymatic or enzymatic reduction und... |
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Quantification of canavanine, 2-aminoethanol, and cyanamide in Aphis craccivora and its host plants, Robinia pseudoacacia and Vicia angustifolia: effects of these compounds on larval survivorship of Harmonia axyridis.
J. Chem. Ecol. 38(12) , 1552-60, (2012) The cowpea aphid Aphis craccivora that infests the black locust Robinia pseudoacacia shows toxicity to its predator, the multicolored Asian ladybird beetle, Harmonia axyridis. In contrast, the same aphid species that infests the common vetch, Vicia angustifol... |
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Opposite motor responses elicited by ethanol in the posterior VTA: the role of acetaldehyde and the non-metabolized fraction of ethanol.
Neuropharmacology 72 , 204-14, (2013) Recent electrophysiological evidence suggests that ethanol simultaneously exerts opposite effects on the activity of dopamine (DA) neurons in the ventral tegmental area (VTA) through two parallel mechanisms, one promoting and the other reducing the GABA relea... |
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The ethanol metabolite acetaldehyde induces water and salt intake via two distinct pathways in the central nervous system of rats.
Neuropharmacology 99 , 589-99, (2015) The sensation of thirst experienced after heavy alcohol drinking is widely regarded as a consequence of ethanol (EtOH)-induced diuresis, but EtOH in high doses actually induces anti-diuresis. The present study was designed to investigate the introduction mech... |
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[Cyanamide-ethanol reaction induced shock: report of a case and literature review].
Chudoku. Kenkyu. 26(4) , 295-9, (2013) Cyanamide is a known alcohol deterrent, and it may cause severe cyanamide-ethanol reaction if a patient consumes high amounts of alcohol during treatment. We report a rare case of cyanamide-ethanol reaction-induced shock in a 73-year-old man who was taking cy... |
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Cyanamide-mediated Inhibition of N-acetyltransferase 1.
Toxicology 302(1) , 1-10, (2012) Cyanamide has been used for decades for medical intentions in the treatment of alcoholism and for agricultural purposes as a plant growth regulator and bud-breaking agent. Its therapeutic effect is mediated by reversible inhibition of aldehyde dehydrogenase a... |
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Iron-catalyzed formation of 2-aminopyridines from diynes and cyanamides.
J. Org. Chem. 77(17) , 7555-63, (2012) Diynes and cyanamides undergo an iron-catalyzed [2 + 2 + 2] cycloaddition to form highly substituted 2-aminopyridines in an atom-efficient manner that is both high yielding and regioselective. This system was also used to cyclize two terminal alkynes and a cy... |
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Different modes of GH administration influence gene expression in the male rat brain.
J. Endocrinol. 222(2) , 181-90, (2014) The endogenous secretion pattern in males of GH is episodic in rats and in humans, whereas GH administration is usually even. Different types of GH administration have different effects on body mass, longitudinal bone growth, and liver metabolism in rodents, ... |
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Analysis of responses to glyceryl trinitrate and sodium nitrite in the intact chest rat
Nitric Oxide 26(4) , 223-8, (2012) Highlights ► Nitroglycerin/glyceryl trinitrate (GTN) has been used for over 140years. ► Mechanism of action remains unknown. ► GTN metabolizes to 1,2-GDN and nitrite anion. ► Nitrite anion derived from GTN does not produce nitric oxide. |