TRIMETHYLACETIC ANHYDRIDE

TRIMETHYLACETIC ANHYDRIDE Structure
TRIMETHYLACETIC ANHYDRIDE structure
Common Name TRIMETHYLACETIC ANHYDRIDE
CAS Number 1538-75-6 Molecular Weight 186.248
Density 1.0±0.1 g/cm3 Boiling Point 193.0±0.0 °C at 760 mmHg
Molecular Formula C10H18O3 Melting Point N/A
MSDS Chinese USA Flash Point 57.2±0.0 °C
Symbol GHS02 GHS05
GHS02, GHS05
Signal Word Danger

Kinetic resolution of racemic 2-hydroxy-γ-butyrolactones by asymmetric esterification using diphenylacetic acid with pivalic anhydride and a chiral acyl-transfer catalyst.

Org. Lett. 15(6) , 1170-3, (2013)

Various optically active 2-hydroxy-γ-butyrolactone derivatives are produced via the kinetic resolution of racemic 2-hydroxy-γ-butyrolactones with diphenylacetic acid using pivalic anhydride and (R)-benzotetramisole ((R)-BTM), a chiral acyl-transfer catalyst. ...

The concept of superactive esters. Could peptide synthesis be improved by inventing superactive esters?

Int. J. Pept. Protein Res. 43 , 312, (1994)

According to the concept presented, esters forming an amide (peptide) bond by the mechanism SN#DN or SN#*DN involving fast decay of the tetrahedral intermediate may behave as 'superactive acylating reagents'. These should render coupling involving less reacti...

Observation and elimination of N-acetylation of oligonucleotides prepared using fast-deprotecting phosphoramidites and ultra-mild deprotection.

Bioorg. Med. Chem. Lett. 11(9) , 1105-1107, (2001)

Commercially available 'fast-deprotecting' phosphoramidites are useful for synthesizing oligonucleotides containing alkali-sensitive nucleotides. However, N-acetylated oligonucleotides were observed during solid-phase synthesis using 'fast-deprotecting' phosp...

New synthetic substrates of mammalian nucleotide excision repair system.

Nucleic Acids Res. 41 , e123, (2013)

DNA probes for the studies of damaged strand excision during the nucleotide excision repair (NER) have been designed using the novel non-nucleosidic phosphoramidite reagents that contain N-[6-(9-antracenylcarbamoyl)hexanoyl]-3-amino-1,2-propandiol (nAnt) and ...

Structural Basis for Substrate Specificity in Adenosylcobalamin-dependent Isobutyryl-CoA Mutase and Related Acyl-CoA Mutases.

J. Biol. Chem. 290 , 26882-98, (2015)

Acyl-CoA mutases are a growing class of adenosylcobalamin-dependent radical enzymes that perform challenging carbon skeleton rearrangements in primary and secondary metabolism. Members of this class of enzymes must precisely control substrate positioning to p...

Kinetic resolution of the racemic 2-hydroxyalkanoates using the enantioselective mixed-anhydride method with pivalic anhydride and a chiral acyl-transfer catalyst.

Chemistry 16(1) , 167-72, (2010)

A variety of optically active 2-hydroxyalkanoates and the corresponding 2-acyloxyalkanoates are produced by the kinetic resolution of racemic 2-hydroxyalkanoates by using achiral 2,2-diarylacetic acid with hindered carboxylic anhydrides as the coupling reagen...

Single-step, quantitative derivatization of amino, carboxyl, and hydroxyl groups in iodothyronine amino acids with ethanolic pivalic anhydride containing 4-dimethylaminopyridine.

Anal. Biochem. 153(1) , 159-65, (1986)

Reaction of thyroxine with ethanol and pivalic anhydride in the presence of 4-dimethylaminopyridine quantitatively forms N,O-dipivalyl thyroxine ethyl ester. Other iodothyronines react similarly and the procedure is moisture insensitive. Apparently this react...

Bull. Chem. Soc. Jpn. 67 , 210, (1994)

Pharmacol. Res. 10 , 68, (1993)

Aust. J. Chem. 60 , 75, (2007)