bis(trimethylsilyl)trifluoroacetamide
bis(trimethylsilyl)trifluoroacetamide structure
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Common Name | bis(trimethylsilyl)trifluoroacetamide | ||
|---|---|---|---|---|
| CAS Number | 25561-30-2 | Molecular Weight | 257.401 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 170.0±50.0 °C at 760 mmHg | |
| Molecular Formula | C8H18F3NOSi2 | Melting Point | -10°C | |
| MSDS | Chinese USA | Flash Point | 56.6±30.1 °C | |
| Symbol |
GHS02, GHS05 |
Signal Word | Danger | |
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The dual FAAH/MAGL inhibitor JZL195 has enhanced effects on endocannabinoid transmission and motor behavior in rats as compared to those of the MAGL inhibitor JZL184.
Pharmacol. Biochem. Behav. 124 , 153-9, (2014) The biological actions of the endocannabinoids anandamide and 2-arachidonoyl glycerol (2-AG) are terminated by enzymatic hydrolysis of these lipids via fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), respectively. While several selective... |
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Direct silylation of Trypanosoma brucei metabolites in aqueous samples and their GC-MS/MS analysis.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 967 , 134-8, (2014) A simple two-step method for the derivatization of polar compounds (lactate, alanine, glycerol, succinate and glucose) using hexamethyldisilazane (HMDS) and N,O-bis(trimethylsilyl)trifluoroacetamide (BSTFA) was developed. This method allows direct derivatizat... |
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Cardiovascular disease-related parameters and oxidative stress in SHROB rats, a model for metabolic syndrome.
PLoS ONE 9(8) , e104637, (2014) SHROB rats have been suggested as a model for metabolic syndrome (MetS) as a situation prior to the onset of CVD or type-2 diabetes, but information on descriptive biochemical parameters for this model is limited. Here, we extensively evaluate parameters rela... |
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Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1).
PLoS ONE 10 , e0141252, (2015) Cytochrome P450c17 (P450 17A1, CYP17A1) is a critical enzyme in the synthesis of androgens and is now a target enzyme for the treatment of prostate cancer. Cytochrome P450c17 can exhibit either one or two physiological enzymatic activities differentially regu... |
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Overcoming the equivalent-chain-length rule with pH-zone-refining countercurrent chromatography for the preparative separation of fatty acids.
Anal. Bioanal. Chem 407 , 5503-11, (2015) Purification of individual fatty acids from vegetable oils by preparative liquid chromatography techniques such as countercurrent chromatography (CCC) is a challenging task due to the equivalent-chain-length (ECL) rule. It implies that one double bond equals ... |
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Free radical scavenging activity and comparative metabolic profiling of in vitro cultured and field grown Withania somnifera roots.
PLoS ONE 10(4) , e0123360, (2015) Free radical scavenging activity (FRSA), total phenolic content (TPC), and total flavonoid content (TFC) of in vitro cultured and field grown Withania somnifera (Ashwagandha) roots were investigated. Withanolides analysis and comprehensive metabolic profiling... |
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Targeted metabolomics in the expanded newborn screening for inborn errors of metabolism.
Mol. Biosyst. 11 , 1525-35, (2015) Inborn errors of metabolism are genetic disorders due to impaired activity of enzymes, transporters, or cofactors resulting in accumulation of abnormal metabolites proximal to the metabolic block, lack of essential products or accumulation of by-products. Man... |
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Characterization of in vitro metabolites of JWH-018, JWH-073 and their 4-methyl derivatives, markers of the abuse of these synthetic cannabinoids
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 957 , 68-76, (2014) • Optimization of a suitable extraction protocol for alkylindoles and their metabolites from biological fluids. • Detection of alkylindoles and their metabolites by means of the GC/MS method adopted by UNODC. • In vitro incubation with human liver microsomes ... |
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Multiresidue method for the determination of pharmacologically active substances in egg and honey using a continuous solid-phase extraction system and gas chromatography-mass spectrometry.
Food Chem. 178 , 63-9, (2015) A sensitive, selective, efficient gas chromatography-mass spectrometry method for the simultaneous determination of 22 pharmacologically active substances (antibacterials, nonsteroidal antiinflammatories, antiseptics, antiepileptics, lipid regulators, β-block... |
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Effects of synthetic alkamides on Arabidopsis fatty acid amide hydrolase activity and plant development.
Phytochemistry 110 , 58-71, (2015) Alkamides and N-acylethanolamines (NAEs) are bioactive, amide-linked lipids that influence plant development. Alkamides are restricted to several families of higher plants and some fungi, whereas NAEs are widespread signaling molecules in both plants and anim... |