Semicarbazide hydrochloride
Semicarbazide hydrochloride structure
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Common Name | Semicarbazide hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 563-41-7 | Molecular Weight | 111.531 | |
| Density | 1.286g/cm3 | Boiling Point | 235.3ºC at 760 mmHg | |
| Molecular Formula | CH6ClN3O | Melting Point | 175-177 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 66.5ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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A selective biomarker for confirming nitrofurazone residues in crab and shrimp using ultra-performance liquid chromatography-tandem mass spectrometry.
Anal. Bioanal. Chem 407 , 8971-7, (2015) Reliably detecting nitrofurazone (NFZ) residues in farmed crab and shrimp was previously hindered by lack of appropriately specific analytical methodology. Parent NFZ rapidly breaks down in meat, and the commonly used side-chain metabolite, semicarbazide (SEM... |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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Rapid detection of economic adulterants in fresh milk by liquid chromatography-tandem mass spectrometry.
J. Chromatogr. A. 1288 , 10-20, (2013) A method to aid in the detection of the economically driven adulteration of fresh milk with a range of small, nitrogen containing compounds, including melamine, ammeline, ammelide, cyanuric acid, allantoin, thiourea, urea, biuret, triuret, semicarbazide, amin... |
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Fortified versus incurred residues: extraction of furazolidinone metabolite from prawn.
Anal. Bioanal. Chem 407 , 4535-40, (2015) Most methods reported in the literature for determination of nitrofuran metabolites use the same extraction and derivatisation conditions to hydrolyse and extract the protein-bound residues from animal tissue. While undertaking certification of reference mate... |
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Inhibition of semicarbazide-sensitive amine oxidase attenuates myocardial ischemia-reperfusion injury in an in vivo rat model.
Leuk. Res. 88 , 302-6, (2011) This study tested the hypothesis that the inhibition of semicarbazide-sensitive amine oxidase (SSAO) after ischemia could attenuate myocardial ischemia-reperfusion (I/R) injury.Anesthetized male Sprague-Dawley rats underwent myocardial I/R injury. Saline, sem... |
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SSAO substrates exhibiting insulin-like effects in adipocytes as a promising treatment option for metabolic disorders.
Future Med. Chem. 2(12) , 1735-49, (2010) Benzylamine exerts insulin-like effects in adipocytes (e.g., glucose uptake and antilipolysis) and improves glucose handling in rodents.In murine adipocytes, benzylamine mimics another insulin action: it enhances apelin expression in a manner that is blocked ... |
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Assessment of the determination of azodicarbonamide and its decomposition product semicarbazide: investigation of variation in flour and flour products.
J. Agric. Food Chem. 59(17) , 9313-8, (2011) Azodicarbonamide, as a bleaching agent and improving agent, is a permitted food additive in certain countries and can be determined by high-performance liquid chromatography. However, it partially degrades with the heat of processing to form trace amounts of ... |
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Semicarbazide is non-specific as a marker metabolite to reveal nitrofurazone abuse as it can form under Hofmann conditions.
Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 26(1) , 47-56, (2009) Detecting illegal nitrofurazone treatment of food-producing animals has been undermined by the reliance on semicarbazide as a marker metabolite for analysis because, during processing, semicarbazide forms in a variety of foods not exposed to nitrofurazone by ... |
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Extracellular serotonin level in the basolateral nucleus of the amygdala and dorsal periaqueductal gray under unconditioned and conditioned fear states: Anin vivomicrodialysis study
Brain Res. 1294 , 106-15, (2009) Serotonin (5-HT) plays a key role in the neural circuitry mediating unconditioned and conditioned fear responses related to panic and generalized anxiety disorders. The basolateral nucleus of the amygdala (BLA) and the dorsal periaqueductal gray (dPAG) appear... |
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Comparative studies by IR, Raman, and surface-enhanced Raman spectroscopy of azodicarbonamide, biurea and semicarbazide hydrochloride.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 114 , 80-4, (2013) Azodicarbonamide is widely applied in the food industry as a new flour gluten fortifier in China, Canada, the United States, and some other countries, whose metabolites of biurea and semicarbazide hydrochloride are reaction products during baking. In this stu... |