Pyronaridine tetraphosphate
Pyronaridine tetraphosphate structure
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Common Name | Pyronaridine tetraphosphate | ||
|---|---|---|---|---|
| CAS Number | 76748-86-2 | Molecular Weight | 910.030 | |
| Density | 1.357g/cm3 | Boiling Point | 657.2ºC at 760 mmHg | |
| Molecular Formula | C29H44ClN5O18P4 | Melting Point | 233-236° (dec) | |
| MSDS | Chinese USA | Flash Point | 351.3ºC | |
| Symbol |
GHS07, GHS08 |
Signal Word | Warning | |
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JPC-2997, a new aminomethylphenol with high in vitro and in vivo antimalarial activities against blood stages of Plasmodium.
Antimicrob. Agents Chemother. 59(1) , 170-7, (2014) 4-(tert-Butyl)-2-((tert-butylamino)methyl)-6-(6-(trifluoromethyl)pyridin-3-yl)-phenol (JPC-2997) is a new aminomethylphenol compound that is highly active in vitro against the chloroquine-sensitive D6, the chloroquine-resistant W2, and the multidrug-resistant... |
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In vitro interactions between piperaquine, dihydroartemisinin, and other conventional and novel antimalarial drugs.
Antimicrob. Agents Chemother. 50 , 2883-2885, (2006) In an in vitro assessment of antimalarial combinations, dihydroartemisinin (DHA) showed no interaction or was mildly antagonistic when combined with piperaquine, pyronaridine, or naphthoquine. Interactions between 4-aminoquinolines and related drugs were also... |
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In vitro activities of piperaquine and other 4-aminoquinolines against clinical isolates of Plasmodium falciparum in Cameroon.
Antimicrob. Agents Chemother. 47 , 1391-1394, (2003) The spread of chloroquine-resistant Plasmodium falciparum calls for a constant search for new drugs. The in vitro activity of piperaquine, a new Chinese synthetic drug belonging to the bisquinolines, was evaluated in 103 fresh clinical isolates of P. falcipar... |