pterostilbene
pterostilbene structure
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Common Name | pterostilbene | ||
|---|---|---|---|---|
| CAS Number | 537-42-8 | Molecular Weight | 256.296 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 420.5±35.0 °C at 760 mmHg | |
| Molecular Formula | C16H16O3 | Melting Point | 89-92ºC | |
| MSDS | Chinese USA | Flash Point | 208.1±25.9 °C | |
| Symbol |
GHS05, GHS09 |
Signal Word | Danger | |
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Pterostilbene and allopurinol reduce fructose-induced podocyte oxidative stress and inflammation via microRNA-377.
Free Radic. Biol. Med. 83 , 214-26, (2015) High dietary fructose is an important causative factor in the development of metabolic syndrome-associated glomerular podocyte oxidative stress and injury. Here, we identified microRNA-377 (miR-377) as a biomarker of oxidative stress in renal cortex of fructo... |
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Anti-proliferative effect of pterostilbene on rat hepatoma cells in culture.
Cytotechnology 67 , 671-80, (2015) Pterostilbene, a methoxylated analogue of resveratrol, is a natural compound primarily found in blueberries and several types of grapes. However, little is known about the effect of pterostilbene on the proliferation of hepatoma cells and its modes of actions... |
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Involvement of the Nrf2 pathway in the regulation of pterostilbene-induced apoptosis in HeLa cells via ER stress.
J. Pharmacol. Sci. 126(3) , 216-29, (2014) Among the various cancer cell lines, HeLa cells were found to be sensitive to pterostilbene (Pte), a compound that is enriched in small fruits such as grapes and berries. However, the mechanism involved in the cytotoxicity of Pte has not been fully characteri... |
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Orally administrated pterostilbene attenuates acute cerebral ischemia-reperfusion injury in a dose- and time-dependent manner in mice.
Pharmacol. Biochem. Behav. 135 , 199-209, (2015) Pterostilbene (3,5-dimethoxy-4-hydroxystilbene) is a component of blueberry. It has been reported that long-term treatment with blueberry has a neuroprotective effect. However, it has not been reported whether pterostilbene is effective in attenuating cerebra... |
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Pterostilbene inhibits triple-negative breast cancer metastasis via inducing microRNA-205 expression and negatively modulates epithelial-to-mesenchymal transition.
J. Nutr. Biochem. 26 , 675-85, (2015) Breast cancer is the leading cause of cancer-related deaths among females in economically developing countries. Greater than 95% of breast malignancies are of epithelial origin; the induction of epithelial-to-mesenchymal transition (EMT) has been shown to ini... |
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Syringetin suppresses osteoclastogenesis mediated by osteoblasts in human lung adenocarcinoma.
Oncol. Rep. 34 , 617-26, (2015) Bone metastasis in lung cancer results in an unfavorable outcome for patients by not only impairing the quality of life, yet also increasing the cancer-related death rates. In the present study, we discuss a novel treatment strategy that may benefit these pat... |
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Pterostilbene suppresses oral cancer cell invasion by inhibiting MMP-2 expression.
Expert Opin. Ther. Targets 18(10) , 1109-20, (2014) Polyphenol compounds, present in a wide variety of natural plants, exhibit antioxidant and free radical scavenging ability and induce apoptosis in various cancer cells. However, the effect of pterostilbene on oral cancer cell metastasis has not been clarified... |
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Pterostilbene inhibits dimethylnitrosamine-induced liver fibrosis in rats.
Food Chem. 138(2-3) , 802-7, (2013) Pterostilbene, found in grapes and berries, exhibits pleiotropic effects, including anti-inflammatory, antioxidant, and anti-proliferative activities. This study was conducted to investigate the effect of pterostilbene on liver fibrosis and the potential unde... |
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Amphiphilic graft copolymers from end-functionalized starches: synthesis, characterization, thin film preparation, and small molecule loading.
Biomacromolecules 15(8) , 2944-51, (2014) End-functionalized macromolecular starch reagents, prepared by reductive amination, were grafted onto a urethane-linked polyester-based backbone using copper-catalyzed azide-alkyne cycloaddition (CuAAC) chemistry to produce novel amphiphilic hybrid graft copo... |
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Long term induction by pterostilbene results in autophagy and cellular differentiation in MCF-7 cells via ROS dependent pathway.
Mol. Cell. Endocrinol. 355(1) , 25-40, (2012) This study shows the effect of pterostilbene on intracellular neutral lipid accumulation in MCF-7 breast cancer cells leading to growth arrest and autophagy. On exposing the breast cancer cells with 30 μM pterostilbene for 72 h there was almost 2-folds increa... |