Aceclofenac
Aceclofenac structure
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Common Name | Aceclofenac | ||
|---|---|---|---|---|
| CAS Number | 89796-99-6 | Molecular Weight | 354.185 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 486.0±45.0 °C at 760 mmHg | |
| Molecular Formula | C16H13Cl2NO4 | Melting Point | 149-153°C | |
| MSDS | Chinese USA | Flash Point | 247.8±28.7 °C | |
| Symbol |
GHS06, GHS09 |
Signal Word | Danger | |
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Development and implication of methodology for aceclofenac in pure and pharmaceutical formulations by microwave assisted spectrophotometry.
Pak. J. Pharm. Sci. 26(1) , 169-73, (2013) A simple, fast and cost effective method for determination of aceclofenac in pure and tablet formulations has been developed and validated. The method is based on formation of stable blue coloured complex (λmax = 740nm) of Aceclofenac with ammonium molybdate ... |
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Electrospun zein/eudragit nanofibers based dual drug delivery system for the simultaneous delivery of aceclofenac and pantoprazole.
Int. J. Pharm. 438(1-2) , 117-22, (2012) Electrospun composite zein/eudragit nanofibers were developed with an aim to deliver two different classes of drugs simultaneously that would restrict/compensate the adverse effects of non-steroidal anti-inflammatory drugs (NSAIDs). Co-administration of proto... |
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Absolute bioavailability and metabolism of aceclofenac in rats.
Arch. Pharm. Res. 38(1) , 68-72, (2015) Aceclofenac is one of the most popular analgesic and anti-inflammatory drugs used for the relief of pain, rheumatoid arthritis, and osteoarthritis. To date, no intravenous preparation of aceclofenac has been developed because of its poor water solubility. In ... |
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Aceclofenac-loaded chitosan-tamarind seed polysaccharide interpenetrating polymeric network microparticles.
Colloids Surf. B Biointerfaces 105 , 303-9, (2013) The present work deals with the preparation, characterization and evaluation of glutaraldehyde cross-linked chitosan-tamarind seed polysaccharide (TSP) interpenetrating polymeric network (IPN) microparticles for prolonged aceclofenac release. The drug entrapm... |
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Nanomiemgel--a novel drug delivery system for topical application--in vitro and in vivo evaluation.
PLoS ONE 9(12) , e115952, (2014) The objective of this study was to formulate and evaluate a unique matrix mixture (nanomiemgel) of nanomicelle and nanoemulsion containing aceclofenac and capsaicin using in vitro and in vivo analyses and to compare it to a marketed formulation (Aceproxyvon).... |
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Development and validation of packed column supercritical fluid chromatographic technique for quantification of chlorzoxazone, paracetamol and aceclofenac in their individual and combined dosage forms.
J. Chromatogr. Sci. 50(9) , 769-74, (2012) A reproducible, rapid and sensitive method has been developed for the assay of chlorzoxazone (CHL), paracetamol (PCM) and aceclofenac (ACE) in their combined solid dosage forms using packed-column supercritical fluid chromatography (SFC). The analytes were re... |
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Oil-entrapped sterculia gum-alginate buoyant systems of aceclofenac: development and in vitro evaluation.
Colloids Surf. B Biointerfaces 104 , 268-75, (2013) The current investigation deals with the development and optimization of oil-entrapped sterculia gum-alginate buoyant beads containing aceclofenac by ionotropic emulsion-gelation technique using 3(2) factorial design. The effect of polymer to drug ratio and s... |
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Drug-induced Sweet's syndrome by aceclofenac.
Cutan. Ocul. Toxicol. 30(4) , 315-6, (2011) Sweet's syndrome (SS) or acute febrile neutrophilic dermatosis is a reactive process that presents in different clinical settings and ranges from classical (idiopathic), malignancy associated or drug induced. The authors describe a 51-year-old Caucasian woman... |
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Effect of aceclofenac on pharmacokinetic of phenytoin.
Pak. J. Pharm. Sci. 25(2) , 295-9, (2012) Aceclofenac is presently most commonly prescribed analgesic for chronic pain and inflammatory conditions. In clinical practice, phenytoin and aceclofenac are used in a chronic condition of generalized seizure with concomitant chronic pain. Hence there are cha... |
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Aceclofenac delivery by microencapsulation using LBL self-assembly for delayed release.
Pak. J. Pharm. Sci. 24(4) , 495-502, (2011) Colonic targeting has gained increasing interest over the past years, not just for the transport of drugs for the treatment of local diseases associated with the colon but also for its potential for transporting peptides and proteins, particularly low molecul... |