Cosmosiin

Cosmosiin Structure
Cosmosiin structure
Common Name Cosmosiin
CAS Number 578-74-5 Molecular Weight 432.378
Density 1.6±0.1 g/cm3 Boiling Point 788.9±60.0 °C at 760 mmHg
Molecular Formula C21H20O10 Melting Point 230-237ºC
MSDS Chinese USA Flash Point 280.7±26.4 °C

Mesophyll distribution of 'antioxidant' flavonoid glycosides in Ligustrum vulgare leaves under contrasting sunlight irradiance.

Ann. Bot. 104(5) , 853-61, (2009)

Flavonoids have the potential to serve as antioxidants in addition to their function of UV screening in photoprotective mechanisms. However, flavonoids have long been reported to accumulate mostly in epidermal cells and surface organs in response to high sunl...

Antioxidant and antigenotoxic properties of compounds isolated from Marrubium deserti de Noé

Food Chem. Toxicol. 49(12) , 3328-35, (2011)

Highlights ► We present here the purification of 13 compounds from an MeOH extract of Marrubium deserti. ► We measure antioxidant, genotoxic and antigenotoxic activites of six phenolic compounds. ► Two isolated compounds are original. ► We could observe some ...

Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.

Bioorg. Med. Chem. 18 , 28-35, (2010)

The applicability of the newly developed RM1 and PM6 methods implemented in the semiempirical quantum chemistry mopac2009 software package in modeling free radical scavenging activity of flavonoids was examined. Bond dissociation enthalpy (BDE) of OH groups c...

CHMIS-C: a comprehensive herbal medicine information system for cancer.

J. Med. Chem. 48 , 1481-8, (2005)

A comprehensive herbal medicine information system for cancer (CHMIS-C) has been developed. The current version of the database integrates information on more than 200 anticancer herbal recipes that have been used for the treatment of different types of cance...

Analysis of the erythroid differentiation effect of flavonoid apigenin on K562 human chronic leukemia cells.

Chem. Biol. Interact. 220 , 269-77, (2014)

The erythroid differentiation-inducing effect of apigenin and its derivatives on human chronic myeloid leukemia K562 has been reported but the functional group in its structure responsible for the effect has not yet been elucidated. Here, we determined the mo...

Multivariate QSAR study on the antimutagenic activity of flavonoids against 3-NFA on Salmonella typhimurium TA98.

Eur. J. Med. Chem. 45 , 4562-9, (2010)

A quantitative structure-activity relationship (QSAR) study of twenty flavonoid derivatives with antimutagenic activity against 3-nitrofluoranthene (3-NFA) was performed by Partial Least Squares (PLS), using Ordered Predictors Selection (OPS) algorithm for va...

Structure-activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP).

Bioorg. Med. Chem. 19 , 2090-102, (2011)

Flavonoids are an interesting group of natural products ubiquitously present in human diet. Their consumption has been associated with various and differing beneficial health effects. However, several flavonoids have been reported to inhibit the breast cancer...

Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities.

Bioorg. Med. Chem. 17 , 6816-23, (2009)

Five flavonols (3, 5, and 9-11) were isolated from Rhodiola rosea, and compared with commercially available flavonoids (1, 2, 4, 6-8, and 12-14) to facilitate analysis of their structure-activity relationship (SAR). All compounds (1-14) showed neuraminidase i...

Triterpenoids and flavonoids from celery (Apium graveolens).

J. Nat. Prod. 72 , 1563-7, (2009)

Three new triterpenoids, 11,21-dioxo-2beta,3beta,15alpha-trihydroxyurs-12-ene-2-O-beta-D-glucopyranoside (1), 11,21-dioxo-3beta,15alpha,24-trihydroxyurs-12-ene-24-O-beta-D-glucopyranoside (2), and 11,21-dioxo-3beta,15alpha,24-trihydroxyolean-12-ene-24-O-beta-...

Achillea millefolium L. s.l. -- is the anti-inflammatory activity mediated by protease inhibition?

J. Ethnopharmacol. 113(2) , 312-7, (2007)

Achillea millefolium L. s.l. is traditionally used not only in the treatment of gastro-intestinal and hepato-biliary disorders, but also as an antiphlogistic drug. As various proteases, for instance human neutrophil elastase (HNE) and matrix metalloproteinase...