A Versatile and Efficient Ligand for Copper??Catalyzed Formation of C N, C O, and P C Bonds: Pyrrolidine??2??Phosphonic Acid Phenyl Monoester

…, Y Jin, H Fu, Y Jiang, Y Zhao

Index: Rao, Honghua; Jin, Ying; Fu, Hua; Jiang, Yuyang; Zhao, Yufen Chemistry - A European Journal, 2006 , vol. 12, # 13 p. 3636 - 3646

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Citation Number: 319

Abstract

Abstract A new and readily available bidentate ligand, namely, pyrrolidine-2-phosphonic acid phenyl monoester (PPAPM), has been developed for the copper-catalyzed formation of C [BOND] N, C [BOND] O, and P [BOND] C bonds, and various N-, O-, and P-arylation products were synthesized in good to excellent yields by using the CuI/PPAPM catalyst system. Addition of the PPAPM ligand greatly increases the reactivity of the copper ...