6-Hexanolactone
6-Hexanolactone structure
|
Common Name | 6-Hexanolactone | ||
|---|---|---|---|---|
| CAS Number | 502-44-3 | Molecular Weight | 114.142 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 225.4±8.0 °C at 760 mmHg | |
| Molecular Formula | C6H10O2 | Melting Point | -1 °C | |
| MSDS | Chinese USA | Flash Point | 109.4±0.0 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Summary: 6-Hexano-6-lactone, also known as ε-己内酯, has a molecular formula of C6H10O2 and a molecular weight of 114.142. It appears as a transparent colorless liquid that may turn yellow over time. The melting point is -1 °C and the boiling point is 225.4±8.0 °C. It is mainly used for synthesizing rubber, fiber, and resin, and also for producing caprolactam, adhesives, coatings, etc. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | hexano-6-lactone |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 225.4±8.0 °C at 760 mmHg |
| Melting Point | -1 °C |
| Molecular Formula | C6H10O2 |
| Molecular Weight | 114.142 |
| Flash Point | 109.4±0.0 °C |
| Exact Mass | 114.068077 |
| PSA | 26.30000 |
| LogP | 0.36 |
| Vapour density | 3.9 (vs air) |
| Vapour Pressure | 0.1±0.4 mmHg at 25°C |
| Index of Refraction | 1.439 |
| InChIKey | PAPBSGBWRJIAAV-UHFFFAOYSA-N |
| SMILES | O=C1CCCCCO1 |
| Water Solubility | >1000 MG/L (20 ºC) |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P280-P305 + P351 + P338-P337 + P313 |
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/38 |
| Safety Phrases | S26-S39-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | MO8400000 |
| HS Code | 2932209090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 10 | |
|---|---|
| DownStream 10 | |
CAS#:124-04-9
CAS#:1191-25-9
CAS#:108-94-1
CAS#:629-11-8
CAS#:108-93-0
CAS#:627-93-0
CAS#:4547-43-7
CAS#:5299-60-5
CAS#:110-82-7
CAS#:930-68-7
CAS#:109359-36-6
CAS#:112375-42-5
CAS#:4286-55-9
CAS#:4224-70-8
CAS#:592-90-5
CAS#:35444-44-1
CAS#:41796-80-9
CAS#:404-86-4This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2932209090 |
|---|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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In vitro evaluation of effects of sustained anti-TNF release from MPEG-PCL-MPEG and PCL microspheres on human rheumatoid arthritis synoviocytes.
J. Biomater. Appl. 29(4) , 524-42, (2014) Anti-tumor necrosis factor α (TNFα) drugs such as etanercept (ETN) have been mostly used in systemic treatment of rheumatoid arthritis. To eliminate the side effects in long-term treatments and to ach... |
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The imaging and the fractal metrology of chimeric liposomal Drug Delivery nano Systems: the role of macromolecular architecture of polymeric guest.
J. Liposome Res. 24(3) , 223-9, (2014) The major advance of mixed liposomes (the so-called chimeric systems) is to control the size, structure, and morphology of these nanoassemblies, and therefore, system colloidal properties, with the ai... |
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Polymeric nanoparticles-embedded organogel for roxithromycin delivery to hair follicles.
Eur. J. Pharm. Biopharm. 88(1) , 75-84, (2014) Drug delivery into hair follicles with the use of nanoparticles (NPs) is gaining more importance as drug-loaded NPs may accumulate in hair follicle openings. The aim was to develop and evaluate a plur... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Oxepan-2-on |
| ε-Caprolactone |
| 6-hydroxyhexanoic acid, ε-lactone |
| E-CAPROLACTONE |
| e-Hexanolactone |
| ε-Hexanolactone |
| UNII-56RE988L1R |
| 6-Caprolactone monomer |
| ε-Hexalactone |
| 6-hydroxyhexanoic acid lactone |
| EINECS 207-938-1 |
| 6-Hexanolactone |
| 2-Oxepanone |
| Hexanoic acid, ε-lactone |
| caprolactone |
| oxepan-2-one |
| Epsilon-Caprolactone Monomer |
| MFCD00003267 |
| 1,6-hexanolide |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the boiling point of hexano-6-lactone? |
| A: Boiling point of hexano-6-lactone is 225.4±8.0 °C at 760 mmHg. |
| Q: How is the water solubility of hexano-6-lactone? |
| A: Water solubility of hexano-6-lactone: >1000 MG/L (20 ºC). |
| Q: What are the upstream materials of hexano-6-lactone? |
| A: Related upstream materials(CAS) of hexano-6-lactone: 124-04-9;1191-25-9;108-94-1;629-11-8;108-93-0;627-93-0;4547-43-7;5299-60-5;110-82-7;930-68-7. |
| Q: What is the CAS number of hexano-6-lactone? |
| A: CAS number of hexano-6-lactone is 502-44-3. |
| Q: What is the molecular weight of hexano-6-lactone? |
| A: Molecular weight of hexano-6-lactone is 114.142. |
| Q: What is the SMILES notation of hexano-6-lactone? |
| A: SMILES notation of hexano-6-lactone is O=C1CCCCCO1. |
| Q: What is the LogP of hexano-6-lactone? |
| A: LogP of hexano-6-lactone is 0.36. |
| Q: What is the InChIKey of hexano-6-lactone? |
| A: InChIKey of hexano-6-lactone is PAPBSGBWRJIAAV-UHFFFAOYSA-N. |
| Q: What is the polar surface area (PSA) of hexano-6-lactone? |
| A: Polar surface area (PSA) of hexano-6-lactone is 26.30000. |
| Q: What are the downstream products of hexano-6-lactone? |
| A: Related downstream products(CAS) of hexano-6-lactone: 109359-36-6;112375-42-5;4286-55-9;4224-70-8;592-90-5;35444-44-1;4547-43-7;41796-80-9;5299-60-5;404-86-4. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |
| Henan Tianfu Chemical Co., Ltd. |