IDO-IN-5
Modify Date: 2024-01-08 20:12:25
IDO-IN-5 structure
|
Common Name | IDO-IN-5 | ||
|---|---|---|---|---|
| CAS Number | 1402837-79-9 | Molecular Weight | 316.370 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 555.4±35.0 °C at 760 mmHg | |
| Molecular Formula | C18H21FN2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 289.7±25.9 °C | |
Use of IDO-IN-5IDO-IN-5 (NLG-1489) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1489, has an IC50 of 1-10 μM. |
| Name | trans-4-{(1R)-2-[(5R)-6-Fluoro-5H-imidazo[5,1-a]isoindol-5-yl]-1-hydroxyethyl}cyclohexanol |
|---|---|
| Synonym | More Synonyms |
| Description | IDO-IN-5 (NLG-1489) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1489, has an IC50 of 1-10 μM. |
|---|---|
| Related Catalog | |
| Target |
IDO:1-10 μM (IC50) |
| In Vitro | IDO-IN-5 (Compound 1487) is an indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 1-10 μM (this is the concentration of IDO-IN-5 at which inhibits 50% of enzymatic activity using recombinant human IDO)[1]. |
| References |
[1]. Mario Mautino, et al. Fused imidazole derivatives useful as ido inhibitors. WO 2012142237 A1. |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 555.4±35.0 °C at 760 mmHg |
| Molecular Formula | C18H21FN2O2 |
| Molecular Weight | 316.370 |
| Flash Point | 289.7±25.9 °C |
| Exact Mass | 316.158691 |
| LogP | 1.28 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.683 |
| Storage condition | 2-8℃ |
| 5H-Imidazo[5,1-a]isoindole-5-ethanol, 6-fluoro-α-(trans-4-hydroxycyclohexyl)-, (αR,5R)- |
| trans-4-{(1R)-2-[(5R)-6-Fluoro-5H-imidazo[5,1-a]isoindol-5-yl]-1-hydroxyethyl}cyclohexanol |
| IDO-IN-5 |