Mcl1-IN-12

Modify Date: 2024-01-02 16:21:05

Mcl1-IN-12 structure	Common Name	Mcl1-IN-12
	CAS Number	2042211-12-9	Molecular Weight	803.00
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₅H₄₆N₄O₆S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Mcl1-IN-12

Mcl1-IN-12 (Compound F) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively. Anti-tumor activity[1].

Name	Mcl1-IN-12

Description	Mcl1-IN-12 (Compound F) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively. Anti-tumor activity[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Bcl-2 Family Research Areas >> Cancer
Target	Ki: 0.29 (Mcl-1), 3.1 μM (Bcl-2)[1]
References	[1]. Wang M, et al. Design, synthesis, and activity evaluation of selective inhibitors of anti-apoptotic Bcl-2 proteins: The effects on the selectivity of the P1 pockets in the active sites. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5207-5211.

Molecular Formula	C₄₅H₄₆N₄O₆S₂
Molecular Weight	803.00