Name | p-hydroxybenzyl alcohol |
---|---|
Synonyms |
4-(Hydroxymethyl)benzolol
(4-Hydroxyphenyl)methanol Gastrodigenin p-Methylolphenol 4-hydroxymethyl-phenol PARA-ALCOHOLPHENOL 4-Hydroxybenzyl alcohol 4-hydroxybenzyl-alcohol Benzyl alcohol, p-hydroxy- (8CI) p-(Hydroxymethyl)phenol p-Hydroxybenzyl 4-(Hydroxymethyl)phenol RARECHEM AL BD 0098 EINECS 210-768-0 Benzenemethanol, 4-hydroxy- Benzyl alcohol, p-hydroxy- 4-METHYLOLPHENOL benzyl alcohol, 4-hydroxy- P-HYDROXYBENZYL ALCOHOL MFCD00004658 4-HYDROXY-BENZYL-ALCOHOL α-Hydroxy-p-cresol FEMA 3987 Bisoprolol Impurity 19 |
Description | 4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants. Anti-inflammatory, anti-oxidant, anti-nociceptive activity. Neuroprotective effect. Inhibitor of tumor angiogenesis and growth[1][2][3][4]. |
---|---|
Related Catalog | |
In Vitro | 4-Hydroxybenzyl alcohol inhibits proliferation of eEND2 cells and suppresses the migration of eEND2 cells, accompanied by inhibition of actin filament reorganization[2]. 4-Hydroxybenzyl alcohol induces apoptotic death of tumor cells[3]. |
In Vivo | 4-Hydroxybenzyl alcohol possesses antiangiogenic, anti-inflammatory and anti-nociceptive activity possibly via its down-regulating activity on NO production[1]. 4-Hydroxybenzyl alcohol (200 mg/kg) efficiently inhibits growth and angiogenesis of developing tumors[3]. 4-Hydroxybenzyl alcohol ameliorates ischemic injury induced by transient focal cerebral ischemia in rats, and this neuroprotective effect may be partly related to attenuate apoptosis pathway[4]. |
References |
Density | 1.2±0.1 g/cm3 |
---|---|
Boiling Point | 252.0±0.0 °C at 760 mmHg |
Melting Point | 114-122 °C(lit.) |
Molecular Formula | C7H8O2 |
Molecular Weight | 124.137 |
Flash Point | 145.8±15.0 °C |
Exact Mass | 124.052429 |
PSA | 40.46000 |
LogP | 0.30 |
Vapour Pressure | 0.0±0.5 mmHg at 25°C |
Index of Refraction | 1.596 |
Storage condition | 2-8°C |
Symbol |
GHS07 |
---|---|
Signal Word | Warning |
Hazard Statements | H319 |
Precautionary Statements | P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xi: Irritant; |
Risk Phrases | R36/37/38 |
Safety Phrases | S26-S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
RTECS | DA4796800 |
HS Code | 29072900 |
Precursor 9 | |
---|---|
DownStream 10 | |
HS Code | 2907299090 |
---|---|
Summary | 2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0% |