1639139-65-3

1639139-65-3 structure
1639139-65-3 structure
  • Name: CL2E-SN38
  • Chemical Name: CL2E-SN38
  • CAS Number: 1639139-65-3
  • Molecular Formula: C86H118N14O24
  • Molecular Weight: 1731.94
  • Create Date: 2022-06-18 14:41:11
  • Modify Date: 2025-08-26 19:26:36
  • CL2E-SN-38, a highly releasable and structurally stable antibody-SN-38-conjugate, is a part of the antibody drug conjugate (ADC). SN-38, the active metabolite of Irinotecan from camptothecins, is an Topoisomerase I inhibitor[1].

Name CL2E-SN38
Description CL2E-SN-38, a highly releasable and structurally stable antibody-SN-38-conjugate, is a part of the antibody drug conjugate (ADC). SN-38, the active metabolite of Irinotecan from camptothecins, is an Topoisomerase I inhibitor[1].
Related Catalog
References

[1]. Lianqi Liu, et al. Synthesis and evaluation of highly releasable and structurally stable antibody-SN-38-conjugates. Drug Deliv. 2021 Dec;28(1):2603-2617.

Molecular Formula C86H118N14O24
Molecular Weight 1731.94
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