CL2E-SN38

Modify Date: 2024-07-17 18:15:26

CL2E-SN38 Structure
CL2E-SN38 structure
Common Name CL2E-SN38
CAS Number 1639139-65-3 Molecular Weight 1731.94
Density N/A Boiling Point N/A
Molecular Formula C86H118N14O24 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CL2E-SN38


CL2E-SN-38, a highly releasable and structurally stable antibody-SN-38-conjugate, is a part of the antibody drug conjugate (ADC). SN-38, the active metabolite of Irinotecan from camptothecins, is an Topoisomerase I inhibitor[1].

 Names

Name CL2E-SN38

 CL2E-SN38 Biological Activity

Description CL2E-SN-38, a highly releasable and structurally stable antibody-SN-38-conjugate, is a part of the antibody drug conjugate (ADC). SN-38, the active metabolite of Irinotecan from camptothecins, is an Topoisomerase I inhibitor[1].
Related Catalog
References

[1]. Lianqi Liu, et al. Synthesis and evaluation of highly releasable and structurally stable antibody-SN-38-conjugates. Drug Deliv. 2021 Dec;28(1):2603-2617.

 Chemical & Physical Properties

Molecular Formula C86H118N14O24
Molecular Weight 1731.94