1331868-55-3
1331868-55-3 structure
- Name: JMN3-003
- Chemical Name: JMN3-003
- CAS Number: 1331868-55-3
- Molecular Formula: C24H22ClN3O2S
- Molecular Weight: 451.969
- Create Date: 2022-07-01 15:15:06
- Modify Date: 2024-04-05 09:46:34
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JMN3-003 is a host-directed inhibitor with potent antiviral activity against a panel of myxovirus family members with EC50 of 10-70 nM.JMN3-003 shows activity against MeV at 170 (viral CPE-reduction assay) and 30 nM (virus yield reduction assay) and does not display any detectable acute cytotoxicity.JMN3-003 also shows superb antiviral activity against a selection of clinical-relevant paramyxovirus (RSV, MuV, and HPIV3) and orthomyxovirus (influenza) family members.
| Name | JMN3-003 |
|---|
| Description | JMN3-003 is a host-directed inhibitor with potent antiviral activity against a panel of myxovirus family members with EC50 of 10-70 nM.JMN3-003 shows activity against MeV at 170 (viral CPE-reduction assay) and 30 nM (virus yield reduction assay) and does not display any detectable acute cytotoxicity.JMN3-003 also shows superb antiviral activity against a selection of clinical-relevant paramyxovirus (RSV, MuV, and HPIV3) and orthomyxovirus (influenza) family members. |
|---|---|
| References | 1. Sun A, et al. ACS Med Chem Lett. 2011 Aug 23;2(11):798-803. |
| Molecular Formula | C24H22ClN3O2S |
|---|---|
| Molecular Weight | 451.969 |