JMN3-003

Modify Date: 2024-04-05 09:46:34

JMN3-003 Structure
JMN3-003 structure
Common Name JMN3-003
CAS Number 1331868-55-3 Molecular Weight 451.969
Density N/A Boiling Point N/A
Molecular Formula C24H22ClN3O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JMN3-003


JMN3-003 is a host-directed inhibitor with potent antiviral activity against a panel of myxovirus family members with EC50 of 10-70 nM.JMN3-003 shows activity against MeV at 170 (viral CPE-reduction assay) and 30 nM (virus yield reduction assay) and does not display any detectable acute cytotoxicity.JMN3-003 also shows superb antiviral activity against a selection of clinical-relevant paramyxovirus (RSV, MuV, and HPIV3) and orthomyxovirus (influenza) family members.

 Names

Name JMN3-003

 JMN3-003 Biological Activity

Description JMN3-003 is a host-directed inhibitor with potent antiviral activity against a panel of myxovirus family members with EC50 of 10-70 nM.JMN3-003 shows activity against MeV at 170 (viral CPE-reduction assay) and 30 nM (virus yield reduction assay) and does not display any detectable acute cytotoxicity.JMN3-003 also shows superb antiviral activity against a selection of clinical-relevant paramyxovirus (RSV, MuV, and HPIV3) and orthomyxovirus (influenza) family members.
References 1. Sun A, et al. ACS Med Chem Lett. 2011 Aug 23;2(11):798-803.

 Chemical & Physical Properties

Molecular Formula C24H22ClN3O2S
Molecular Weight 451.969