663214-48-0

663214-48-0 structure

663214-48-0 structure

Name: Antiproliferative agent-13
Chemical Name: Antiproliferative agent-13
CAS Number: 663214-48-0
Molecular Formula: C₂₀H₁₈N₂O₆
Molecular Weight: 382.37
Catalog: Research Areas Cancer
Create Date: 2022-10-11 13:04:09
Modify Date: 2024-04-05 16:02:59
Antiproliferative agent-13 (compound 16c) shows an antiproliferative activity against human A375 cells with an IC50 value of 32.7 nM. Antiproliferative agent-13 can be used for the research of cancer[1].

Name	Antiproliferative agent-13

Description	Antiproliferative agent-13 (compound 16c) shows an antiproliferative activity against human A375 cells with an IC50 value of 32.7 nM. Antiproliferative agent-13 can be used for the research of cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50: 32.7 nM (A375 cells)[1]
In Vitro	Antiproliferative agent-13 (0-10 μM; 72 h) affects proliferation of human A375 melanoma cells[1]. Cell Proliferation Assay[1] Cell Line: A375 melanoma cell line Concentration: 0-10000 nM Incubation Time: 72 hours Result: Showed an anti-proliferative activity to human A375 melanoma cells with an IC50 value of 32.7 nM.
References	[1]. Zhang H, et al. Design, synthesis and characterization of potent microtubule inhibitors with dual anti-proliferative and anti-angiogenic activities. Eur J Med Chem. 2018 Sep 5;157:380-396

Molecular Formula	C₂₀H₁₈N₂O₆
Molecular Weight	382.37