Antiproliferative agent-13

Modify Date: 2024-04-05 16:02:59

Antiproliferative agent-13 Structure
Antiproliferative agent-13 structure
Common Name Antiproliferative agent-13
CAS Number 663214-48-0 Molecular Weight 382.37
Density N/A Boiling Point N/A
Molecular Formula C20H18N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antiproliferative agent-13


Antiproliferative agent-13 (compound 16c) shows an antiproliferative activity against human A375 cells with an IC50 value of 32.7 nM. Antiproliferative agent-13 can be used for the research of cancer[1].

 Names

Name Antiproliferative agent-13

 Antiproliferative agent-13 Biological Activity

Description Antiproliferative agent-13 (compound 16c) shows an antiproliferative activity against human A375 cells with an IC50 value of 32.7 nM. Antiproliferative agent-13 can be used for the research of cancer[1].
Related Catalog
Target

IC50: 32.7 nM (A375 cells)[1]

In Vitro Antiproliferative agent-13 (0-10 μM; 72 h) affects proliferation of human A375 melanoma cells[1]. Cell Proliferation Assay[1] Cell Line: A375 melanoma cell line Concentration: 0-10000 nM Incubation Time: 72 hours Result: Showed an anti-proliferative activity to human A375 melanoma cells with an IC50 value of 32.7 nM.
References

[1]. Zhang H, et al. Design, synthesis and characterization of potent microtubule inhibitors with dual anti-proliferative and anti-angiogenic activities. Eur J Med Chem. 2018 Sep 5;157:380-396

 Chemical & Physical Properties

Molecular Formula C20H18N2O6
Molecular Weight 382.37