2389016-82-2

2389016-82-2 structure

Name: Antiproliferative agent-6
Chemical Name: Antiproliferative agent-6
CAS Number: 2389016-82-2
Molecular Formula: C₂₁H₁₄ClFN₆
Molecular Weight: 404.83
Catalog: Research Areas Cancer
Create Date: 2022-07-02 12:18:51
Modify Date: 2024-01-10 18:43:45
Antiproliferative against-6 (compound 8a) is a potent antitumor agent. Antiproliferative against-6 has antiproliferative activity against cancer cell lines HCT116, MCF-7, H460 and non-tumor aneuploid immortal keratinocyte HaCaT cells with GI50s of 0.5 μM, 2 μM, 0.7 μM and 3.5 μM, respectively[1].

Name	Antiproliferative agent-6

Description	Antiproliferative against-6 (compound 8a) is a potent antitumor agent. Antiproliferative against-6 has antiproliferative activity against cancer cell lines HCT116, MCF-7, H460 and non-tumor aneuploid immortal keratinocyte HaCaT cells with GI50s of 0.5 μM, 2 μM, 0.7 μM and 3.5 μM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	GI50: 0.5 μM (HCT116), 2 μM (MCF-7), 0.7 μM (H460), 3.5 μM (HaCaT)[1]
References	[1]. Meščić Macan A, et al. Synthesis, antiproliferative activity and DNA/RNA-binding properties of mono- and bis-(1,2,3-triazolyl)-appended benzimidazo[1,2-a]quinoline derivatives. Eur J Med Chem. 2020;185:111845.

Molecular Formula	C₂₁H₁₄ClFN₆
Molecular Weight	404.83