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572-32-7

572-32-7 structure
572-32-7 structure
  • Name: Ayanin
  • Chemical Name: 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxychromen-4-one
  • CAS Number: 572-32-7
  • Molecular Formula: C18H16O7
  • Molecular Weight: 344.315
  • Catalog: Natural product Flavonoids
  • Create Date: 2017-11-29 00:38:53
  • Modify Date: 2025-08-21 17:39:27
  • Ayanin is a bioflavonoid isolated from Croton schiedeanus Schlecht. Ayanin is a non-selective phosphodiesterase1-4 inhibitor and can be used for the study of respiratory disease,such as allergic asthma et al[1].

Name 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxychromen-4-one
Synonyms 3',5-Dihydroxy-3,4',7-trimethoxyflavone
3,4',7-O-trimethylquercetin
4H-1-Benzopyran-4-one, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxy-
5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxy-4H-chromen-4-one
quercetin-3,4',7-trimethyl ether
3,7,4'-trimethylquercetin
3,7,4'-trimethoxy-5,3'-dihydroxyflavone
5,3'-Dihydroxy-3,7,4'-trimethoxyflavone
Ayanin
3,7,4'-Tri-O-methylquercetin
3',5-dihydroxy-3,4',7-trimethoxy-flavone
Description Ayanin is a bioflavonoid isolated from Croton schiedeanus Schlecht. Ayanin is a non-selective phosphodiesterase1-4 inhibitor and can be used for the study of respiratory disease,such as allergic asthma et al[1].
Related Catalog
Target

PDE2A

PDE4

In Vitro Ayanin inhibits interleukin (IL)-4 production from purified basophils with an IC50 value of 2.2 μM[1].
References

[1]. Fei-Peng Lee, et al.  Ayanin, a Non-Selective Phosphodiesterase 1-4 Inhibitor, Effectively Suppresses Ovalbumin-Induced Airway Hyperresponsiveness Without Affecting xylazine/ketamine-induced Anesthesia. Eur J Pharmacol. 2010 Jun 10;635(1-3):198-203.

Density 1.5±0.1 g/cm3
Boiling Point 600.8±55.0 °C at 760 mmHg
Melting Point 173℃
Molecular Formula C18H16O7
Molecular Weight 344.315
Flash Point 221.5±25.0 °C
Exact Mass 344.089600
PSA 98.36000
LogP 2.43
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.654
Hazard Codes Xi
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