572-32-7

572-32-7 structure

Name: Ayanin
Chemical Name: 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxychromen-4-one
CAS Number: 572-32-7
Molecular Formula: C₁₈H₁₆O₇
Molecular Weight: 344.315
Catalog: Natural product Flavonoids
Create Date: 2017-11-29 00:38:53
Modify Date: 2024-01-08 21:58:18
Ayanin is a bioflavonoid isolated from Croton schiedeanus Schlecht. Ayanin is a non-selective phosphodiesterase1-4 inhibitor and can be used for the study of respiratory disease,such as allergic asthma et al[1].

Name	5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxychromen-4-one
Synonyms	3',5-Dihydroxy-3,4',7-trimethoxyflavone 3,4',7-O-trimethylquercetin 4H-1-Benzopyran-4-one, 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxy- 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxy-4H-chromen-4-one quercetin-3,4',7-trimethyl ether 3,7,4'-trimethylquercetin 3,7,4'-trimethoxy-5,3'-dihydroxyflavone 5,3'-Dihydroxy-3,7,4'-trimethoxyflavone Ayanin 3,7,4'-Tri-O-methylquercetin 3',5-dihydroxy-3,4',7-trimethoxy-flavone

Description	Ayanin is a bioflavonoid isolated from Croton schiedeanus Schlecht. Ayanin is a non-selective phosphodiesterase1-4 inhibitor and can be used for the study of respiratory disease,such as allergic asthma et al[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Research Areas >> Inflammation/Immunology
Target	PDE2A PDE4
In Vitro	Ayanin inhibits interleukin (IL)-4 production from purified basophils with an IC50 value of 2.2 μM[1].
References	[1]. Fei-Peng Lee, et al. Ayanin, a Non-Selective Phosphodiesterase 1-4 Inhibitor, Effectively Suppresses Ovalbumin-Induced Airway Hyperresponsiveness Without Affecting xylazine/ketamine-induced Anesthesia. Eur J Pharmacol. 2010 Jun 10;635(1-3):198-203.

Hazard Codes	Xi