480-37-5

480-37-5 structure

Name: Pinocembrin-7-methyl ether
Chemical Name: pinostrobin
CAS Number: 480-37-5
Molecular Formula: C₁₆H₁₄O₄
Molecular Weight: 270.280
Catalog: Natural product Flavonoids
Create Date: 2018-02-27 08:00:00
Modify Date: 2024-01-08 17:25:58
Pinostrobin is a flavonoid can be found in many plants, and has anti-oxidant, anti-inflammatory, anti-cancer and neuroprotective properties. Pinostrobin is a potent PCSK9 inhibitor and inhibits the catalytic activity of PCSK9. Pinostrobin is a promising agent for cholesterol regulation and lipid management[1].

Name	pinostrobin
Synonyms	Dihydrotectochrysin 4H-1-Benzopyran-4-one, 2,3-dihydro-5-hydroxy-7-methoxy-2-phenyl-, (S)- Pinostrobin 2-Phenyl-5-hydroxy-7-methoxy-2,3-dihydro-4H-1-benzopyran-4-one (S)-5-Hydroxy-7-methoxy-2-phenyl-2,3-dihydro-4H-chromen-4-one Pistrobin Pinocembrin-7-methyl ether 5-Hydroxy-7-methoxy-2-phenyl-chroman-4-one (2S)-5-Hydroxy-7-methoxy-2-phenyl-2,3-dihydro-4H-chromen-4-one 2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one Pinostobin 4H-1-Benzopyran-4-one, 2,3-dihydro-5-hydroxy-7-methoxy-2-phenyl-, (2S)-

Description	Pinostrobin is a flavonoid can be found in many plants, and has anti-oxidant, anti-inflammatory, anti-cancer and neuroprotective properties. Pinostrobin is a potent PCSK9 inhibitor and inhibits the catalytic activity of PCSK9. Pinostrobin is a promising agent for cholesterol regulation and lipid management[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease Research Areas >> Inflammation/Immunology
Target	IC50: PCSK9[1]
References	[1]. Gao WY, et al. Pinostrobin Inhibits Proprotein Convertase Subtilisin/Kexin-type 9 (PCSK9) Gene Expression through the Modulation of FoxO3a Protein in HepG2 Cells.J Agric Food Chem. 2018 Jun 20;66(24):6083-6093.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2932999099

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%