Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Fmoc-L-Leucine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

35661-60-0

35661-60-0 structure

Name: Fmoc-Leu-OH
Chemical Name: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid
CAS Number: 35661-60-0
Molecular Formula: C₂₁H₂₃NO₄
Molecular Weight: 353.412
Catalog: Biochemical Amino acids and their derivatives Leucine derivative
Create Date: 2018-04-23 08:00:00
Modify Date: 2026-06-30 17:12:16
Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity[1].

Name	(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid
Synonyms	N-ALPHA-FMOC-L-LEUCINE N-((9H-Fluoren-9-ylmethoxy)carbonyl)-L-leucine FMoc-L-leucine FMoc-Leu-OH FMOC-D-LEU N-9-FLUORENYLMETHYLOXYCBONYL-L-LEUCINE FMOC-LEU-OH G N-ALPHA-(9-FLUORENYLMETHOXYCBONYL)-L-LEUCINE Fmoc-D-leucine-OH N-FMOC-LEU-OH N-Fmoc-D-leucine FMOC-L-Leucine //BP FMOC-L-LEU-OH PP-GAMMA ACTIVATOR N-Fmoc-L-leucine (S)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)amino)-4-Methylpentanoic acid N-[(9H-Fluorene-9-yl)methoxycbonyl]leucine N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-leucine EINECS 252-662-7 N-FMOC-L-LEU (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-methylpentanoic acid (S)-2-[[(9H-Fluorene-9-yl)methoxycbonyl]amino]-4-methylpentanoic acid FMOC-L-LEU-OH MONOHYDRATE Fmoc-L-leucine Fmoc-L-Leu-OH Fmoc-L-leucin N-(9-FLUORENYLMETHOXYCBONYL)-L-LEUCINE N-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-L-leucine, (2S)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanoic acid FMOC-LEU-OH (9H-Fluoren-9-yl)MethOxy]carbonyl Leu-OH F-L-LEU FMOC-L-LEUCINE extrapure L-Leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl] N-[(9H-FLUOREN-9-YLMETHOXY)carbonyl]-L-LEUCINE (((9H-fluoren-9-yl)methoxy)carbonyl)-L-leucine 9-FLUORENYLMETHOXYCBONYL-L-LEUCINE D-LeuFmoc-OH 2-[[(9H-FLUOREN-9-YLMETHOXY)carbonyl]AMINO]-4-METHYLPENTANOIC ACID N-ALPHA-(9-FLUORENYLMETHYLOXYCBONYL)-L-LEUCINE (2R)-2-amino-3-[4-[4-[(2R)-2-cboxy-2-(9H-fluoren-9-ylmethoxycbonylamino)ethyl]phenyl]phenyl]propanoic acid Tocris-0675 L-LEUCINE-N-FMOC FMOC-L-LEUCINE N-(9-Fluorenylmethoxycbonyl)-L-leucine Fmoc-L-leucine 2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-methylpentanoic acid N-Fmoc-L-leucine Fmoc-D-Leu-OH L-Leucine-1-13C-N-FMOC FMOC-LEUCINE N-Fmoc-L-leucine Fmoc-Leu-OH N-(fluorenyl-9-methoxycbonyl)leucine Fmoc-Leucine-OH D-Fmoc-Leu-OH Fmoc-D-Leucine MFCD00037133 FMOC-LEU Fmoc-N-(isobutyl)-glycine Fmoc-N-(isobutyl)-Gly-OH N-(9-Fluorenylmethoxycbonyl)-L-leucine, Fmoc-L-leucine N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-leucine FMoc-Nleu-OH 2-(9H-fFuoren-9-ylmethoxycbonylamino)-4-methylpentanoic acid (2S)-4-Methyl-2-(9H-fluorene-9-ylmethoxycbonylamino)valeric acid FMoc-Leu-OH >= N-FMOC-L-LEUCINE Fmoc-L-leucine (HPLC, Chiral purity) (2S)-2-(9H-fluoren-9-ylmethoxycbonylamino)-4-methylpentanoicaci (S)-2-(N-FMOC-Amino)-4-methylpentanoic acid FMOC-L-LEU Fmoc-Leu-OH Fmoc-Leu-OH

Description	Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR Research Areas >> Metabolic Disease
Target	PPARγ
References	[1]. Rocchi S, et al. A unique PPARgamma ligand with potent insulin-sensitizing yet weak adipogenic activity. Mol Cell. 2001 Oct;8(4):737-47.

Density	1.2±0.1 g/cm3
Boiling Point	559.8±33.0 °C at 760 mmHg
Melting Point	152-156 °C(lit.)
Molecular Formula	C₂₁H₂₃NO₄
Molecular Weight	353.412
Flash Point	292.4±25.4 °C
Exact Mass	353.162720
PSA	75.63000
LogP	4.95
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.583
Storage condition	2~8°C

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2924299090

Precursor 7
28920-43-6 61-90-5 82911-69-1 103321-59-1
1131148-55-4 88744-04-1 102774-86-7
DownStream 10
143744-88-1 217082-60-5 58822-25-6 28540-82-1
86060-88-0 76542-83-1 58970-76-6 103321-59-1
157606-25-2 103478-62-2

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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