77029-83-5

77029-83-5 structure

Name: Hycrecrellin A
Chemical Name: hypocrellin a
CAS Number: 77029-83-5
Molecular Formula: C₃₀H₂₆O₁₀
Molecular Weight: 546.521
Catalog: Natural product Moss
Create Date: 2018-05-23 08:00:00
Modify Date: 2024-01-01 23:24:18
Hypocrellin A, a naturally occurring PKC inhibitor, has many biological and pharmacological properties, such as antitumour, antiviral, antibacterial, and antileishmanial activities. Hypocrellin A is a promising photosensitizer for anticancer photodynamic therapy (PDT)[1][2][3][4].

Name	hypocrellin a
Synonyms	1-Acetyl-2,5,12-trihydroxy-4,8,9,13-tetramethoxy-2-methyl-2,3-dihydro-1H-cyclohepta[ghi]perylene-6,11-dione (1S,2R)-1-Acetyl-2,5,12-trihydroxy-4,8,9,13-tetramethoxy-2-methyl-2,3-dihydro-1H-cyclohepta[ghi]perylene-6,11-dione 1H-Cyclohepta[ghi]perylene-6,11-dione, 1-acetyl-2,3-dihydro-2,5,12-trihydroxy-4,8,9,13-tetramethoxy-2-methyl-, (1S,2R)- 1H-Cyclohepta[ghi]perylene-6,11-dione, 1-acetyl-2,3-dihydro-2,5,12-trihydroxy-4,8,9,13-tetramethoxy-2-methyl- hypocrellin

Description	Hypocrellin A, a naturally occurring PKC inhibitor, has many biological and pharmacological properties, such as antitumour, antiviral, antibacterial, and antileishmanial activities. Hypocrellin A is a promising photosensitizer for anticancer photodynamic therapy (PDT)[1][2][3][4].
Related Catalog	Signaling Pathways >> Epigenetics >> PKC Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> TGF-beta/Smad >> PKC
References	[1]. Dang L, et al. Effects of hypocrellin A on expression of vascular endothelial growth factor and endothelin-1 in human umbilical endothelial cells. Am J Chin Med. 2007;35(4):713-23. [2]. Ma YJ, et al. Enhanced Production of Hypocrellin A in Submerged Cultures of Shiraia bambusicola by Red Light. Photochem Photobiol. 2019 May;95(3):812-822. [3]. Fehr MJ, et al. Roles of oxygen and photoinduced acidification in the light-dependent antiviral activity of hypocrellin A. Biochemistry. 1995 Dec 5;34(48):15845-8. [4]. Ma G, et al. Antimicrobial and antileishmanial activities of hypocrellins A and B. Antimicrob Agents Chemother. 2004 Nov;48(11):4450-2.

Safety Phrases	22-24/25