3262-64-4

3262-64-4 structure
3262-64-4 structure
  • Name: (R)-2-AMINO-3-(PROP-2-YN-1-YLTHIO)PROPANOIC ACID
  • Chemical Name: (2R)-2-amino-3-prop-2-ynylsulfanylpropanoic acid
  • CAS Number: 3262-64-4
  • Molecular Formula: C6H9NO2S
  • Molecular Weight: 159.21
  • Catalog: Signaling Pathways Apoptosis MDM-2/p53
  • Create Date: 2018-11-14 12:48:27
  • Modify Date: 2024-01-02 17:58:54
  • S-Propargylcysteine (SPRC), a structural analog of S-allyl cysteine (SAC), is a slow H2S-releasing compound. S-Propargylcysteine reduces Ca2+ accumulation and inflammatory cytokines, inhibits STAT3, and elevates p53 and Bax. S-Propargylcysteine has anti-inflammatory activity and protects mice against acute pancreatitis. S-Propargylcysteine also has cardioprotective, neuroprotective acitivties[1][2].

Name (2R)-2-amino-3-prop-2-ynylsulfanylpropanoic acid
Synonyms (R)-2-Amino-3-(2-propynylthio)propanoicAcid
(R)-2-Amino-3-(2-propynylthio)propanoic Acid
2-amino-3-prop-2-ynylsulfanyl-propionic acid
S-propargyl cysteine
S-Prop-2-inyl-L-cystein
(R)-2-Amino-3-(prop-2-yn-1-ylthio)propanoic acid
S-2-Propinyl-L-cystein
S-prop-2-ynyl-L-cysteine
S-propargyl-L-cysteine
Description S-Propargylcysteine (SPRC), a structural analog of S-allyl cysteine (SAC), is a slow H2S-releasing compound. S-Propargylcysteine reduces Ca2+ accumulation and inflammatory cytokines, inhibits STAT3, and elevates p53 and Bax. S-Propargylcysteine has anti-inflammatory activity and protects mice against acute pancreatitis. S-Propargylcysteine also has cardioprotective, neuroprotective acitivties[1][2].
Related Catalog
References

[1]. Sidhapuriwala JN, et al. Effects of S-propargyl-cysteine (SPRC) in caerulein-induced acute pancreatitis in mice. PLoS One. 2012;7(3):e32574.  

[2]. Wen YD, et al. The Pharmacological Effects of S-Propargyl-Cysteine, a Novel Endogenous H2S-Producing Compound. Handb Exp Pharmacol. 2015;230:325-36.  

Density 1.284g/cm3
Boiling Point 294.8ºC at 760 mmHg
Melting Point 176-178 °C
Molecular Formula C6H9NO2S
Molecular Weight 159.21
Flash Point 132.1ºC
Exact Mass 159.03500
PSA 88.62000
LogP 0.46500
Index of Refraction 1.57
Hazard Codes Xi
HS Code 2930909090
Precursor  4

DownStream  0

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%