(R)-2-AMINO-3-(PROP-2-YN-1-YLTHIO)PROPANOIC ACID

Modify Date: 2024-01-02 17:58:54

(R)-2-AMINO-3-(PROP-2-YN-1-YLTHIO)PROPANOIC ACID structure	Common Name	(R)-2-AMINO-3-(PROP-2-YN-1-YLTHIO)PROPANOIC ACID
	CAS Number	3262-64-4	Molecular Weight	159.21
	Density	1.284g/cm3	Boiling Point	294.8ºC at 760 mmHg
	Molecular Formula	C₆H₉NO₂S	Melting Point	176-178 °C
	MSDS	N/A	Flash Point	132.1ºC

Use of (R)-2-AMINO-3-(PROP-2-YN-1-YLTHIO)PROPANOIC ACID

S-Propargylcysteine (SPRC), a structural analog of S-allyl cysteine (SAC), is a slow H2S-releasing compound. S-Propargylcysteine reduces Ca2+ accumulation and inflammatory cytokines, inhibits STAT3, and elevates p53 and Bax. S-Propargylcysteine has anti-inflammatory activity and protects mice against acute pancreatitis. S-Propargylcysteine also has cardioprotective, neuroprotective acitivties[1][2].

Name	(2R)-2-amino-3-prop-2-ynylsulfanylpropanoic acid
Synonym	More Synonyms

Description	S-Propargylcysteine (SPRC), a structural analog of S-allyl cysteine (SAC), is a slow H2S-releasing compound. S-Propargylcysteine reduces Ca2+ accumulation and inflammatory cytokines, inhibits STAT3, and elevates p53 and Bax. S-Propargylcysteine has anti-inflammatory activity and protects mice against acute pancreatitis. S-Propargylcysteine also has cardioprotective, neuroprotective acitivties[1][2].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> STAT Signaling Pathways >> JAK/STAT Signaling >> STAT Signaling Pathways >> Apoptosis >> MDM-2/p53 Research Areas >> Inflammation/Immunology
References	[1]. Sidhapuriwala JN, et al. Effects of S-propargyl-cysteine (SPRC) in caerulein-induced acute pancreatitis in mice. PLoS One. 2012;7(3):e32574. [2]. Wen YD, et al. The Pharmacological Effects of S-Propargyl-Cysteine, a Novel Endogenous H2S-Producing Compound. Handb Exp Pharmacol. 2015;230:325-36.

Description

Related Catalog

Signaling Pathways >> Stem Cell/Wnt >> STAT

Signaling Pathways >> JAK/STAT Signaling >> STAT

Signaling Pathways >> Apoptosis >> MDM-2/p53

Research Areas >> Inflammation/Immunology

References

[1]. Sidhapuriwala JN, et al. Effects of S-propargyl-cysteine (SPRC) in caerulein-induced acute pancreatitis in mice. PLoS One. 2012;7(3):e32574.

[2]. Wen YD, et al. The Pharmacological Effects of S-Propargyl-Cysteine, a Novel Endogenous H2S-Producing Compound. Handb Exp Pharmacol. 2015;230:325-36.

Density	1.284g/cm3
Boiling Point	294.8ºC at 760 mmHg
Melting Point	176-178 °C
Molecular Formula	C₆H₉NO₂S
Molecular Weight	159.21
Flash Point	132.1ºC
Exact Mass	159.03500
PSA	88.62000
LogP	0.46500
Index of Refraction	1.57