34316-15-9
34316-15-9 structure
- Name: Chelerythrine
- Chemical Name: chelerythrine
- CAS Number: 34316-15-9
- Molecular Formula: C21H18ClNO4
- Molecular Weight: 348.371
- Catalog: Biochemical Natural product
- Create Date: 2018-06-01 08:00:00
- Modify Date: 2026-07-03 22:58:21
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Chelerythrine is a natural alkaloid, acts as a potent and selective Ca2+/phospholopid-dependent PKC antagonist, with an IC50 of 0.7 μM[1]. Chelerythrine has antitumor, antidiabetic and anti-inflammatory activity[2].
| Name | chelerythrine |
|---|---|
| Synonyms |
Einecs -0
helerythrine chelerythrine/toddaline 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin Chelerythrin Chelerythrine from Macleaya cordata (Willd.) R. Br Chelerythrine, 10 mM in DMSO EINECS 251-930-0 Cheleritrine MFCD00060717 3-9 (Chloride) Chelerythrine chloride Chelerythrine chlori Broussonpapyrine [1,3]Dioxolo[4',5':4,5]benzo[1,2-c]phenanthridinium,1,2-dimethoxy-12-methyl 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium CHELERYTHRINE 17,18-DIMETHOXY-21-METHYL-5,7-DIOXA-21-AZAPENTACYCLO[11.8.0.0^{2,10}.0^{4,8}.0^{14,19}]HENICOSA-1,2,4,9,11,14,16,18,20-NONAEN-21-IUM 1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium 2,3-oxymethanoxy)-5-methyl-7,8-dimethoxybenzo[c]phenanthridine-5-ium Chelerythrine //BP 5 (Hydroxide) Chelerythrine DISCONTINUED. Please see C291880 Chelerythrin-Kation Sibutramine Impurity 7 Chelerythrine (6CI) 1,2-Dimethoxy-N-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride 1,2-Dimethoxy-12-methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridin-12-ium CHELERYTHRINE(TODDALINE)(RG) 1,2-Dimethoxy-12-methyl[1,3]dioxolo[4,5]benzo[1,2-c]phenanthridin-12-ium Chelerythrin chlorid |
| Description | Chelerythrine is a natural alkaloid, acts as a potent and selective Ca2+/phospholopid-dependent PKC antagonist, with an IC50 of 0.7 μM[1]. Chelerythrine has antitumor, antidiabetic and anti-inflammatory activity[2]. |
|---|---|
| Related Catalog | |
| Target |
PKC:0.7 μM (IC50) |
| References |
| Melting Point | 195-205ºC |
|---|---|
| Molecular Formula | C21H18ClNO4 |
| Molecular Weight | 348.371 |
| Exact Mass | 348.123047 |
| PSA | 40.80000 |
| LogP | 0.72060 |
| Storage condition | Desiccate at -20°C |
| Hazard Codes | Xn:Harmful; |
|---|---|
| Risk Phrases | R20/21/22 |
| Safety Phrases | S36/37 |
| HS Code | 2933990090 |
|
~2%
34316-15-9 |
| Literature: Heterocycles, , vol. 20, # 8 p. 1535 - 1539 |
| Precursor 1 | |
|---|---|
| DownStream 3 | |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |