1185166-01-1

1185166-01-1 structure

Name: Metformin D6 hydrochloride
Chemical Name: 3-(diaminomethylidene)-1,1-bis(trideuteriomethyl)guanidine,hydrochloride
CAS Number: 1185166-01-1
Molecular Formula: C₄H₆D₆ClN₅
Molecular Weight: 171.662
Catalog: analytical chemistry Standard Forensic and veterinary standards
Create Date: 2018-04-09 08:00:00
Modify Date: 2024-01-11 08:10:19
Metformin D6 hydrochloride is a deuterium labeled Metformin hydrochloride. Metformin hydrochloride inhibits the mitochondrial respiratory chain in the liver, leading to activation of AMPK, enhancing insulin sensitivity for type 2 diabetes research. Metformin hydrochloride triggers autophagy[1].

Name	3-(diaminomethylidene)-1,1-bis(trideuteriomethyl)guanidine,hydrochloride
Synonyms	Metformin-(dimethyl-d6) hydrochloride N,N-Bis[(H)methyl]imidodicarbonimidic diamide hydrochloride (1:1) Imidodicarbonimidic diamide, N,N-dimethyl-d-, hydrochloride (1:1) Diabex-d6,Glucophage-d6 Diabetosan-d6 Metformin-d6,Hydrochloride N,N-Dimethylimidodicarbonimidic Diamide-d6,Hydrochloride Metiguanide-d6

Description	Metformin D6 hydrochloride is a deuterium labeled Metformin hydrochloride. Metformin hydrochloride inhibits the mitochondrial respiratory chain in the liver, leading to activation of AMPK, enhancing insulin sensitivity for type 2 diabetes research. Metformin hydrochloride triggers autophagy[1].
Related Catalog	Signaling Pathways >> Epigenetics >> AMPK Research Areas >> Cardiovascular Disease Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> PI3K/Akt/mTOR >> AMPK Signaling Pathways >> Autophagy >> Mitophagy Research Areas >> Metabolic Disease
Target	AMPK
References	[1]. Soraya H, et al. Acute treatment with metformin improves cardiac function following NSC 37745 induced myocardial infarction in rats. Pharmacol Rep. 2012;64(6):1476-84.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319
Precautionary Statements	P305 + P351 + P338
Hazard Codes	Xn
Risk Phrases	22-36/38
Safety Phrases	26
RIDADR	NONH for all modes of transport