2'-Deoxy-2'-fluorocytidine

Modify Date: 2024-01-02 21:30:20

2'-Deoxy-2'-fluorocytidine structure	Common Name	2'-Deoxy-2'-fluorocytidine
	CAS Number	10212-20-1	Molecular Weight	245.208
	Density	1.8±0.1 g/cm3	Boiling Point	500.1±60.0 °C at 760 mmHg
	Molecular Formula	C₉H₁₂FN₃O₄	Melting Point	167ºC
	MSDS	N/A	Flash Point	256.2±32.9 °C

Use of 2'-Deoxy-2'-fluorocytidine

2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency of both compounds antiviral effects on CCHFV replication[1].

Name	2'-Deoxy-2'-fluorocytidine
Synonym	More Synonyms

Description	2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency of both compounds antiviral effects on CCHFV replication[1].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection
In Vitro	2'-Deoxy-2'-fluorocytidine has antiviral activities, showing 50% effective concentrations (EC50) of 61 nM and 31 nM against CCHFV and CCHFV/ZsG in Huh7 cells, respectively. And it shows a 50% cytotoxicity concentration (CC50) of >50.0 μM in Huh7 cells[1].
References	[1]. Stephen R Welch, et al. Identification of 2'-deoxy-2'-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus. Antiviral Res. 2017 Nov;147:91-99.

Density	1.8±0.1 g/cm3
Boiling Point	500.1±60.0 °C at 760 mmHg
Melting Point	167ºC
Molecular Formula	C₉H₁₂FN₃O₄
Molecular Weight	245.208
Flash Point	256.2±32.9 °C
Exact Mass	245.081177
PSA	110.60000
LogP	-1.26
Vapour Pressure	0.0±2.9 mmHg at 25°C
Index of Refraction	1.697
Storage condition	2-8°C

2'-Deoxy-2'-fluorocytidine MSDS(Chinese)

Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	26-36
HS Code	2934999090

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DownStream 4
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