[Pro9]-Substance P structure
|
Common Name | [Pro9]-Substance P | ||
|---|---|---|---|---|
| CAS Number | 104486-69-3 | Molecular Weight | 1387.69000 | |
| Density | 1.43g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C66H102N18O13S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of [Pro9]-Substance P[Pro9]-Substance P is a potent, reversible and selective agonist of NK-1 tachykinin receptors with an EC50 of 0.93 nM[1]. |
| Name | arg-pro-lys-pro-gln-gln-phe-phe-pro-leu-met-nh2 |
|---|---|
| Synonym | More Synonyms |
| Description | [Pro9]-Substance P is a potent, reversible and selective agonist of NK-1 tachykinin receptors with an EC50 of 0.93 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
NK1:0.93 nM (EC50) |
| In Vitro | [3H][Pro9]-Substance P can be used as a radio ligand for NK- 1 binding sites[1]. [Pro9]-Substance P stimulates inositol phosphate formation with an efficacy only slightly lower than that of SP (EC50 values of 0.93 ± 0.07 and 0.45 ± 0.06 nM, respectively) on primary cultures of newborn mouse cortical glial cells[1]. |
| Density | 1.43g/cm3 |
|---|---|
| Molecular Formula | C66H102N18O13S |
| Molecular Weight | 1387.69000 |
| Exact Mass | 1386.76000 |
| PSA | 533.14000 |
| LogP | 4.61590 |
| Index of Refraction | 1.669 |
| WGK Germany | 3 |
|---|
| H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Pro-Leu-Met-NH2 |
| 9-L-PROLINE-SUBSTANCE P |
| substance P,Pro(9) |
| RPKPQQFFPLM-NH2 |
| [TYR9]-SUBSTANCE P |
| [Pro9]SP |
| [PRO9] SUBSTANCE P |
| L-Arg-L-Pro-L-Lys-L-Pro-L-Gln-L-Gln-L-Phe-L-Phe-L-Pro-L-Leu-L-Met-NH2 |
| pro(9)-substance |
| [Pro9]-Substance P |