n-Butyl fumarate

Modify Date: 2024-01-02 13:40:29

n-Butyl fumarate structure	Common Name	n-Butyl fumarate
	CAS Number	105-76-0	Molecular Weight	228.285
	Density	1.0±0.1 g/cm3	Boiling Point	280.0±0.0 °C at 760 mmHg
	Molecular Formula	C₁₂H₂₀O₄	Melting Point	-85°C
	MSDS	Chinese USA	Flash Point	136.4±18.2 °C
	Symbol	GHS07, GHS08	Signal Word	Warning

Use of n-Butyl fumarate

Dibutyl maleate, the diester of the Maleic Acid, can be used as an intermediate of pharmaceutical synthesis. Dibutyl maleate can enhance contact sensitization to Fluorescein isothiocyanate in mice[1].

Name	Dibutyl maleate
Synonym	More Synonyms

Description	Dibutyl maleate, the diester of the Maleic Acid, can be used as an intermediate of pharmaceutical synthesis. Dibutyl maleate can enhance contact sensitization to Fluorescein isothiocyanate in mice[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Matsuoka T, et, al. Dibutyl Maleate and Dibutyl Fumarate Enhance Contact Sensitization to Fluorescein Isothiocyanate in Mice. Biol Pharm Bull. 2016;39(2):272-7.

Density	1.0±0.1 g/cm3
Boiling Point	280.0±0.0 °C at 760 mmHg
Melting Point	-85°C
Molecular Formula	C₁₂H₂₀O₄
Molecular Weight	228.285
Flash Point	136.4±18.2 °C
Exact Mass	228.136154
PSA	52.60000
LogP	3.81
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.452
Water Solubility	insoluble
Freezing Point	<-85℃

n-Butyl fumarate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ON0875000

CHEMICAL NAME :: Maleic acid, dibutyl ester

CAS REGISTRY NUMBER :: 105-76-0

BEILSTEIN REFERENCE NO. :: 1726634

LAST UPDATED :: 199806

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C12-H20-O4

MOLECULAR WEIGHT :: 228.32

WISWESSER LINE NOTATION :: 4OV1U1VO4 -C

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 11/27/1963 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) Volume(issue)/page/year: 2,19,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) Volume(issue)/page/year: 2,19,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1029 No. of Facilities: 178 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 4094 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1029 No. of Facilities: 37 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 402 (estimated)

Symbol	GHS07, GHS08
Signal Word	Warning
Hazard Statements	H317-H373
Precautionary Statements	P280
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant
Risk Phrases	R43;R51/53
Safety Phrases	S26-S36-S61-S37-S29-S24
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	ON0875000
Packaging Group	I; II; III
HS Code	2917190090

Precursor 10
CAS#:592-84-7 Butyl formate CAS#:110-16-7 Maleic acid CAS#:147-73-9 mesotartaric acid CAS#:71-36-3 Butanol
CAS#:24761-88-4 (E)-1-butoxy-2-... CAS#:108-31-6 Maleic anhydride CAS#:71-41-0 pentanol CAS#:141-32-2 butyl acrylate
CAS#:109-65-9 1-Bromobutane CAS#:298-12-4 Glyoxylic acid
DownStream 9
CAS#:10042-89-4 Butanedioic aci... CAS#:106-98-9 1-Butene CAS#:71-36-3 Butanol CAS#:6295-06-3 Butyl glyoxylate
CAS#:105-75-9 Dibutyl fumarate CAS#:65817-24-5 dimethyl benzof... CAS#:69425-31-6 tetrabutyl prop... CAS#:5144-51-4 Butanedioic aci...
CAS#:63842-87-5 butoxy-succinic...

HS Code	2917190090
Summary	2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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n-butyl maleate

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: n-Butyl fumarate
Price: ￥128.0/500ml
Purity: 97.0%
Stocking Period: 3 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Dibutyl maleate
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Dibutyl maleate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Dibutyl maleate
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Dibutyl maleate
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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