FR-900359
Modify Date: 2025-08-27 15:16:53
FR-900359 structure
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Common Name | FR-900359 | ||
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| CAS Number | 107530-18-7 | Molecular Weight | 1002.16 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C49H75N7O15 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of FR-900359FR900359 is a depsipeptide selective inhibitor of Gαq/11/14 in mammalia, can inhibits ERK pathway. FR900359 suppresses the proliferation of melanoma cells and decreases of blood pressure. FR900359 also protected against airway hyperreactivity in murine models of allergen sensitization in Ovalbumins(HY-W250978)–induced sensitization model of asthma. FR900359 can be used for cancer and cardiovascular disease research[1][2][3][4]. |
| Name | fr900359 |
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| Description | FR900359 is a depsipeptide selective inhibitor of Gαq/11/14 in mammalia, can inhibits ERK pathway. FR900359 suppresses the proliferation of melanoma cells and decreases of blood pressure. FR900359 also protected against airway hyperreactivity in murine models of allergen sensitization in Ovalbumins(HY-W250978)–induced sensitization model of asthma. FR900359 can be used for cancer and cardiovascular disease research[1][2][3][4]. |
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| Related Catalog | |
| References |
| Molecular Formula | C49H75N7O15 |
|---|---|
| Molecular Weight | 1002.16 |
| Exact Mass | 1001.53000 |
| PSA | 285.69000 |
| LogP | 1.63000 |
| InChIKey | IMXKHFILKMPFGB-ZWYWTTNJSA-N |
| SMILES | C=C1C(=O)NC(C)C(=O)N(C)C(C)C(=O)NC(C(OC(=O)C(NC(=O)CC)C(O)C(C)C)C(C)C)C(=O)N(C)C(C(C)OC)C(=O)OC(C(C)C)C(NC(C)=O)C(=O)OC(Cc2ccccc2)C(=O)N1C |