hCAIX/XII-IN-4

Modify Date: 2024-04-09 12:02:13

hCAIX/XII-IN-4 structure	Common Name	hCAIX/XII-IN-4
	CAS Number	1119200-33-7	Molecular Weight	364.35
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₆N₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of hCAIX/XII-IN-4

hCAIX/XII-IN-4 (compound 6c) is a potent CAIX/XII inhibitor with the Ki values of 4.5 nM, 23.6 nM, >10000 nM and >10000 nM for CAXII, CAIX, CAI and CAⅡ, respectively[1].

Name	hCAIX/XII-IN-4

Description	hCAIX/XII-IN-4 (compound 6c) is a potent CAIX/XII inhibitor with the Ki values of 4.5 nM, 23.6 nM, >10000 nM and >10000 nM for CAXII, CAIX, CAI and CAⅡ, respectively[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase
Target	Ki: 4.5 nM (CAXII), 4.5 nM (CAXII), >10000 nM (CAI), and > 10000 nM (CAⅡ)[1]
References	[1]. Thacker PS, et, al. Design, synthesis and biological evaluation of coumarin linked 1,2,4-oxadiazoles as selective carbonic anhydrase IX and XII inhibitors. Bioorg Chem. 2020 May;98:103739.

Molecular Formula	C₂₀H₁₆N₂O₅
Molecular Weight	364.35