Br-Boc-C2-azido

Modify Date: 2024-01-12 12:47:07

Br-Boc-C2-azido Structure
Br-Boc-C2-azido structure
Common Name Br-Boc-C2-azido
CAS Number 1120364-53-5 Molecular Weight 236.07
Density N/A Boiling Point N/A
Molecular Formula C6H10BrN3O2 Melting Point N/A
MSDS Chinese USA Flash Point >230 °F
Symbol GHS07
GHS07
Signal Word Warning

 Use of Br-Boc-C2-azido


Br-Boc-C2-azido is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Br-Boc-C2-azido
Synonym More Synonyms

 Br-Boc-C2-azido Biological Activity

Description Br-Boc-C2-azido is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C6H10BrN3O2
Molecular Weight 236.07

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
RIDADR NONH for all modes of transport
Flash Point(F) >230 °F
Flash Point(C) >110 °C

 Articles2

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 Synonyms

MFCD28144595
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