Azido-PEG6-C1-Boc

Modify Date: 2024-01-14 23:13:22

Azido-PEG6-C1-Boc Structure
Azido-PEG6-C1-Boc structure
Common Name Azido-PEG6-C1-Boc
CAS Number 297162-49-3 Molecular Weight 421.486
Density N/A Boiling Point N/A
Molecular Formula C18H35N3O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG6-C1-Boc


Azido-PEG6-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG6-CH2CO2t-butyl ester
Synonym More Synonyms

 Azido-PEG6-C1-Boc Biological Activity

Description Azido-PEG6-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C18H35N3O8
Molecular Weight 421.486
Exact Mass 421.242401
LogP 0.04

 Synonyms

AZIDO-PEG6-CH2CO2TBU
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