Boc-C2-NH2

Modify Date: 2024-01-03 18:35:26

Use of Boc-C2-NH2

Boc-C2-NH2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	tert-Butyl 3-aminopropanoate
Synonym	More Synonyms

Description	Boc-C2-NH2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Hazard Codes	Xi
HS Code	2922499990

Precursor 5
CAS#:18605-26-0 TERT-BUTYL 3-((... CAS#:102124-10-7 3-benzylamino-p... CAS#:115-11-7 Isobutylene CAS#:107-95-9 beta-Alanine
CAS#:1663-39-4 tert-Butyl acrylate
DownStream 3
CAS#:18605-26-0 TERT-BUTYL 3-((... CAS#:102124-10-7 3-benzylamino-p... CAS#:174799-89-4 Fmoc-N-(tert-bu...

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

tert-butyl 3-aminopropanoate

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Price: ￥344/100mg

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