Para-Cresidine

Modify Date: 2024-01-10 19:18:51

Para-Cresidine structure	Common Name	Para-Cresidine
	CAS Number	120-71-8	Molecular Weight	137.179
	Density	1.0±0.1 g/cm3	Boiling Point	235.4±20.0 °C at 760 mmHg
	Molecular Formula	C₈H₁₁NO	Melting Point	50-52 °C(lit.)
	MSDS	Chinese USA	Flash Point	102.1±15.0 °C
	Symbol	GHS07, GHS08	Signal Word	Danger

Name	2-Methoxy-5-methylaniline
Synonym	More Synonyms

Density	1.0±0.1 g/cm3
Boiling Point	235.4±20.0 °C at 760 mmHg
Melting Point	50-52 °C(lit.)
Molecular Formula	C₈H₁₁NO
Molecular Weight	137.179
Flash Point	102.1±15.0 °C
Exact Mass	137.084061
PSA	35.25000
LogP	1.55
Vapour density	4.7 (vs air)
Vapour Pressure	0.1±0.5 mmHg at 25°C
Index of Refraction	1.549
Water Solubility	Slightly soluble in hot water.

Para-Cresidine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BZ6720000

CHEMICAL NAME :: o-Anisidine, 5-methyl-

CAS REGISTRY NUMBER :: 120-71-8

BEILSTEIN REFERENCE NO. :: 0637071

LAST UPDATED :: 199806

DATA ITEMS CITED :: 27

MOLECULAR FORMULA :: C8-H11-N-O

MOLECULAR WEIGHT :: 137.20

WISWESSER LINE NOTATION :: ZR C1 FO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1450 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 364 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Brain and Coverings - tumors Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 355 gm/kg/92W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 182 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Brain and Coverings - tumors Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3640 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1607 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7280 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2961 gm/kg/92W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 364 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 437 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 595 mg/kg

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 412,155,1998 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,91,1982 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,91,1982 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FINLAND;Carcinogen JAN 1993 OEL-FRANCE;Carcinogen JAN 1993

Symbol	GHS07, GHS08
Signal Word	Danger
Hazard Statements	H302-H319-H350
Precautionary Statements	P201-P305 + P351 + P338-P308 + P313
Personal Protective Equipment	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T:Toxic;
Risk Phrases	R22;R45
Safety Phrases	S53-S45
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	BZ6720000
Packaging Group	I; II; III
Hazard Class	6.1
HS Code	2922199090

Precursor 8
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DownStream 10
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HS Code	2922299090
Summary	2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Development of QSAR models for predicting hepatocarcinogenic toxicity of chemicals.

Eur. J. Med. Chem. 44 , 3658-64, (2009)

A dataset comprising 55 chemicals with hepatocarcinogenic potency indices was collected from the Carcinogenic Potency Database with the aim of developing QSAR models enabling prediction of the above u...

Biopartitioning micellar chromatography to predict mutagenicity of aromatic amines.

Eur. J. Med. Chem. 42 , 1396-402, (2007)

Mutagenicity is a toxicity endpoint associated with the chronic exposure to chemicals. Aromatic amines have considerable industrial and environmental importance due to their widespread use in industry...

Chromosome 11 allelotypes reflect a mechanism of chemical carcinogenesis in heterozygous p53-deficient mice.

Carcinogenesis 22(1) , 89-98, (2001)

Mice heterozygous for a null p53 allele were administered three well-characterized carcinogens to learn more about mechanisms of carcinogenesis and to evaluate the p53-deficient mouse as a tool for id...

Para-Cresidine

EINECS 204-419-1

6-Methoxy-m-toluidine

2-Methoxy-5-methylbenzenamine

2-Methoxy-5-methylaniline

Cresidine

Benzenamine,2-methoxy-5-methyl

5-Methyl-o-anisidine

Para Cresidine

p-cresidine

MFCD00007815

Benzenamine, 2-methoxy-5-methyl-

2-amino-4-methylanisole

1-amino-2-methoxy-5-methylbenzene

Krezidin

3-Amino-4-methoxytoluene

2-methoxy-5-methyl aniline

5-methyl-2-methoxyaniline

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Para-Cresidine
Price: ￥108.0/25g ￥318.0/100g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-Methoxy-5-methylaniline
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 2-Methoxy-5-methylaniline
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Para-Cresidine

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CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

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